摘要
Fluoride is widely distributed in nature,and it can lead to fluorosis if intake is excessive.In addition to its established effects on the skeleton and teeth,fluoride can also exert toxic effects on the kidneys.Fluoride can induce abnormal renal function in humans and other animals[1-3],but the mechanisms through which fluoride exerts such effects remain obscure.
基金
supported by the National Natural Science Foundation of China Grant No.81703230
the Key Scientific Research Project of Universities in Henan Province Grant No.17A330005。
