摘要
胰岛素抵抗(insulin resistance, IR)是多囊卵巢综合征(polycystic ovary syndrome, PCOS)的重要病理生理改变,在女性代谢和生殖障碍中起着重要作用。维生素D缺乏现象普遍存在于PCOS患者中,并与IR、生育力下降以及心血管疾病等远期并发症相关。本文探讨了维生素D缺乏对PCOS合并IR患者影响的研究进展,以期为PCOS合并IR患者的发病机制、诊断治疗及预防提供新的理论依据。
Insulin resistance(IR),as an important pathophysiological change in polycystic ovary syndrome(PCOS),plays a crucial role in female metabolic and reproductive disorders.Vitamin D deficiency is commonly observed in PCOS patients which is associated with long-term complications such as IR,reproductive disorders and cardiovascular diseases.In this paper,we discuss the research progress on the effect of vitamin D deficiency on PCOS patients with IR,in order to provide a better theoretical basis of the pathological mechanisms,diagnosis and treatment for these patients.
作者
罗颖鎏
王倩
崔趁趁
张翠莲
姜月宁
Luo Yingliu;Wang Qian;Cui Chenchen;Zhang Cuilian;Jiang Yuening(Zhengzhou University People’s Hospital,Henan Provincial People's Hospital,Zhengzhou 450003,China)
出处
《中华生殖与避孕杂志》
CAS
CSCD
北大核心
2020年第6期506-510,共5页
Chinese Journal of Reproduction and Contraception
基金
国家自然科学基金面上项目(81571407)。
