摘要
目的:探讨血清淀粉样蛋白A(SAA)、C-反应蛋白(CRP)与降钙素原(PCT)检测在鉴别诊断小儿细菌感染性疾病与小儿病毒感染性疾病中的应用价值。方法:将2018年3月至2019年3月期间甘肃省第三人民医院收治的76例细菌感染性疾病患儿、50例病毒感染性疾病患儿与同期在该医院进行体检的55例健康儿童作为研究对象。将其中76例细菌感染性疾病患儿设为细菌感染组,将其中50例病毒感染性疾病患儿设为病毒感染组,将其中55例健康儿童设为健康组。对三组儿童血清SAA、CRP与PCT的水平均进行检测,然后比较其检测的结果。结果:细菌感染组患儿血清CRP、PCT和SAA的水平均高于病毒感染组患儿与健康组儿童,差异有统计学意义,P<0.05。病毒感染组患儿血清SAA的水平高于健康组儿童,差异有统计学意义,P<0.05。病毒感染组患儿与健康组儿童血清CRP及PCT的水平相比,差异无统计学意义,P>0.05。结论:对细菌感染性疾病患儿与病毒感染性疾病患儿进行血清SAA、CRP与PCT检测对鉴别诊断其病情具有重要的意义。
Objective:To investigate the application value of serum amyloid A(SAA),C-reactive protein(CRP)and procalcitonin(PCT)in the differential diagnosis of bacterial and viral infectious diseases in children.Methods:76 cases of children with bacterial infections and 50 cases of children with viral infections were admitted to the Third People’s Hospital of Gansu Province from March 2018 to March 2019,as well as 55 healthy children who underwent physical examination in the hospital during the same period.Seventy-six children with bacterial infectious diseases were assigned to the bacterial infection group,50 children with viral infectious diseases were assigned to the viral infection group,and 55 healthy children were assigned to the healthy group.Serum SAA,CRP and PCT levels were measured in the three groups,and then the results were compared.Results:The serum LEVELS of CRP,PCT and SAA in the bacterial infection group were higher than those in the virus infection group and the healthy group,and the difference was statistically significant(P<0.05).The serum SAA level of children in the virus infected group was higher than that of the healthy group,and the difference was statistically significant(P<0.05).There was no significant difference in serum CRP and PCT between the children in the viral infection group and the healthy group(P>0.05).Conclusion:Serum SAA,CRP and PCT tests are of great significance for the differential diagnosis of bacterial and viral diseases.
作者
高志武
李泽慧
柴丽萍
Gao Zhiwu;Li Zehui;Chai Liping(Clinical Laboratory,The Third People’s Hospital of Gansu Province,Lanzhou 730020,China)
关键词
淀粉样蛋白
C-反应蛋白
降钙素原
小儿细菌感染性疾病
小儿病毒感染性疾病
Amyloid protein
C-reactive protein
Procalcitonin
Bacterial infectious diseases in children
Diseases of infantile viral i nfections
