摘要
目的:探讨左甲状腺素钠片治疗妊娠期甲状腺功能减退症(SCH)患者的临床效果。方法:选取2017年8月-2019年7月笔者所在医院收治的68例妊娠期SCH患者,根据随机数字表法分为对照组和观察组,每组34例。对照组接受常规治疗,观察组在对照组基础上接受左甲状腺素钠片治疗。比较两组干预后甲状腺激素(TSH、FT4、FT3)、血清Hcy及叶酸水平,观察两组妊娠并发症(胎儿生长不良、胎盘早剥、妊娠出血)情况。结果:干预后观察组TSH水平明显低于对照组,FT4、FT3水平均明显高于对照组(P<0.05);观察组血清Hcy及叶酸水平均高于对照组(P<0.05);观察组妊娠并发症发生率为5.88%,低于对照组的29.41%(P<0.05)。结论:妊娠期SCH患者应用左甲状腺素钠片可改善甲状腺功能,降低妊娠并发症发生率,值得进一步研究及推广。
Objective:To investigate the clinical effect of Levothyroxine Sodium Tablets in the treatment of subclinical hypothyroidism (SCH) during pregnancy.Method:A total of 68 cases with SCH during pregnancy admitted to our hospital from August 2017 to July 2019 were selected and divided into the control group and the observation group according to the method of random number table,34 cases in each group.The control group received routine treatment,and the observation group received Levothyroxine Sodium Tablets on the basis of the control group.After intervention,thyroid hormone (TSH,FT4,FT3),serum Hcy and folate levels of the two groups were compared,and the pregnancy complications (fetal dysplasia,placental abruption and pregnancy hemorrhage) were observed between the two groups.Result:After intervention,the level of TSH in the observation group were significantly lower than that of the control group,and the levels of FT4 and FT3 were significantly higher than those of the control group (P<0.05).The levels of serum Hcy and folate in the observation group were higher than those of the control group (P<0.05).And the incidence of pregnancy complications of the observation group was 5.88%,which was lower than 29.41% of the control group (P<0.05).Conclusion:Levothyroxine Sodium Tablets can improve thyroid function in patients with SCH during pregnancy,and reduce the incidence of pregnancy complications,which is worthy of further research and promotion.
作者
林亮
LIN Liang(Wuchuan People’s Hospital,Wuchuan 524500,China)
出处
《中外医学研究》
2020年第17期129-131,共3页
CHINESE AND FOREIGN MEDICAL RESEARCH
关键词
左甲状腺素钠片
妊娠期
甲状腺功能减退症
疗效
Levothyroxine Sodium Tablets
Pregnancy
Subclinical hypothyroidism
Curative effect
