摘要
Dear Editor,Huntington’s disease (HD) is an autosomal dominant neurodegenerative disease characterized by movement disorder,progressive dementia,and psychiatric and behavioral changes.It is caused by unstable expanded CAG trinucleotide repeats in exon 1 of the huntingtin (HTT)gene,located on chromosome 4p16.3 [1].
基金
supported by the Key Research and Development Project of Zhejiang Province,China (2019C03039)
the Research Foundation for Distinguished Scholars of Zhejiang University,China(188020193810101/089)。