摘要
目的:探讨正常甲状腺病态综合征(ESS)对高危冠状动脉旁路移植术(CABG)患者重度多器官功能不全事件发生的相关因素。方法:选择北京安贞医院接受高危CABG术从2018年1月1日到2018年12月31日的患者,其中387例(58.7%)冠心病患者CABG术后发生了ESS,272例(41.3%)冠心病患者CABG术后未发生ESS。结果:ESS异常组患者CABG术后各种院内不良事件的发生率较ESS正常组显著提高。同时,ESS异常组的SOFA评分最大值比ESS正常组显著增高[(9.1±3.2)vs.(7.1±2.9),P=0.001]。二分类Logistic回归分析结果显示,CABG术术后ESS与患者严重多器官功能不全的发生,即SOFA评分最大值≥11,相关(OR=2.98,95%CI:1.90~4.65,P<0.0001)。结论:ESS可能是行CABG高危患者的短期预后不良的影响因素,尤其是与患者术后重度多器官功能不全的发生相关。
Objective:The purpose of this cohort study was to investigate the association between euthyroid sick syndrome(ESS)and postoperative multiple organ function in high-risk patients undergoing isolated coronary artery bypass grafting(CABG).Methods:The present study enrolled high-risk patients undergoing CABG from 1 January 2018 to 31 December 2018,including 387(58.7%)patients with ESS and 272(41.3%)patients without ESS.Results:This current study demonstrated that ESS exerted detrimental effects on short-term clinical outcomes in high-risk patients undergoing isolated CABG.Specifically,ESS was independently associated with a higher incidence of SOFA maximum greater than 11.Conclusions:ESS was independently associated with severe multi-organ dysfunction in high-risk patients undergoing CABG.
作者
袁文
王家阳
董然
张魁
翟光耀
YUAN Wen;WANG Jiayang;DONG Ran;ZHANG Kui;ZHAI Guangyao(Department of Comprehensive Medical,Beijing Anzhen Hospital,Capital Medical University,Beijing Institute of Heart,Lung and Blood Vessel Diseases,Beijing 100029,China)
出处
《心肺血管病杂志》
2020年第7期817-821,共5页
Journal of Cardiovascular and Pulmonary Diseases
