摘要
目的应用计算流体动力学(computational fluid dynamics,CFD)方法对电磁驱动搏动式灌注血泵流场进行仿真分析,通过改进泵头结构改善血液在血泵的流动状态,提升其抗溶血性能。方法应用Fluent 17. 0分析泵头结构变化对泵内流场的影响,通过血液流入和流出的4次仿真实验,分析内部液体的流线分布、中轴面上的湍流动能分布、血液流经泵头的压力损失和模型表面受到的切应力。结果在4次实验中,泵头入口与出口管路对称且与对称轴的夹角α=30°时,液体流线无明显紊乱,湍流程度较低;实验1中压力损失最小,为376. 8 Pa;实验1、2中的最大切应力分别为258. 6、302. 8 Pa,符合压力损失和溶血程度等血泵生物力学性能要求。选择α=30°模型为该电磁驱动搏动式灌注血泵的泵头结构,并通过3D打印技术进行制作。结论经过对泵头的优化分析,血泵溶血性能得到改善。研究结果可以运用到新型电磁驱动搏动式灌注血泵的设计与实验中。
Objective The flow field of electromagnetically driven pulsating perfusion blood pump was simulated by computational fluid dynamics(CFD)method,and the flow state of blood in blood pump was improved by modifying the structure of pump head,so as to improve its anti-hemolytic performance.Methods The influences of changes in pump head structure on flow field in the pump were analyzed by using Fluent 17.0.Four simulation experiments were carried out to analyze streamline distributions of the internal liquid,the turbulent flow energy distribution on axis of the model,pressure loss of blood flowing through the pump head and shear stress on surface of the model.Results In the four experiments,when the angle between the inlet and outlet of the pump head was symmetrical and the angle between the pump head and the symmetrical axis(α)was 30°,there was no obvious disturbance in the flow line and the turbulence degree was low.In Experiment 1,the pressure loss was 376.8 Pa,with the minimum value.The maximum shear stress in Experiment 2 and 3 was 258.6 Pa and 302.8 Pa,respectively,which met the biomechanical requirements of blood pump such as pressure loss and hemolysis.The model withα=30°was selected as pump head structure of the pulsating blood pump driven by electromagnetic force,and was fabricated by 3D printing technology.Conclusions By optimization of the pump head,the hemolysis performance of the blood pump was improved.The research results can be applied to the design and experiment of a new electromagnetic drive pulse perfusion blood pump.
作者
赵圣功
葛斌
方旭晨
李刚
徐毅骁
魏凌轩
ZHAO Shenggong;GE Bin;FANG Xuchen;LI Gang;XU Yixiao;WEI Lingxuan(School of Medical Instrument and Food Engineering,University of Shanghai for Science and Technology,Shanghai 200093,China;Department of Critical Care Medicine,East City Hospital Affiliated to University of Shanghai for Science and Technology,Shanghai 200438,China)
出处
《医用生物力学》
EI
CAS
CSCD
北大核心
2020年第3期296-303,310,共9页
Journal of Medical Biomechanics
基金
上海市大学生创新计划基金项目(SH2016118)。
关键词
搏动式血泵
机械灌注
泵头
计算流体动力学
数值模拟
pulsating blood pump
mechanical perfusion
pump head
computational fluid dynamics(CFD)
numerical simulation
