摘要
通过近30年国内外相关文献分析,系统总结了冬虫夏草在呼吸系统炎性疾病治疗中的药理和临床研究进展。冬虫夏草及其相关产品在肺部疾病治疗的药理和临床研究广泛,药用历史悠久,总结发现其主要通过调节机体免疫、减少肺部渗出、抑制炎症反应而发挥疗效。为加快冬虫夏草抗呼吸系统炎性疾病的中药新药开发及应用提供了参考资料。
Chinese cordyceps and related products have been investigated for pharmaceutical treatment and clinical trials against respiratory inflammatory diseases in past 30 years,and dozens of research papers have been published. Their therapy and mechanism of action were summarized based on those studies and literature analysis. It was found that Chinese cordyceps has a wide range of researches on the treatment of lung diseases,and has a long history of medicinal use,and a curative effect mainly by regulating the bodys immunity,reducing lung exudation and inhibiting inflammatory reactions. This paper enhances the comprehensive understanding of Chinese cordyceps in therapy of respiratory inflammatory and provides reference for further research and development of new Chinese medicines based on Chinese cordyceps.
作者
邱健健
张奕敏
李光荣
李文佳
陈欣欣
杨子峰
QIU Jianjian;ZHANG Yimin;LI Guangrong;LI Wenjia;CHEN Xinxin;YANG Zifeng(Key Laboratory of State Administration of Traditional Chinese Medicine,Sunshine Lake Pharma Co.,LTD.,Dongguan 523850,China;State Key Laboratory of Respiratory Disease,National Clinical Research Center for Respiratory Disease,Guangzhou Institute of Respiratory Health,the First Affiliated Hospital of Guangzhou Medical University,Guangzhou 510000,China;Macao University of Science and Technology,State Key Laboratory of Quality Research in Chinese Medi-cines,Macao 00853,China;KingMed Virology Diagnostic&Translational Center,National Clinical Research Center of Respiratory Disease-Research Center for Clinical Virology,State Key La-boratory of Respiratory Disease-Research Laboratory for Clinical Virology,Guangzhou 510000,China)
出处
《菌物研究》
CAS
2020年第2期86-92,共7页
Journal of Fungal Research
基金
国家重点研发计划项目(2018YFC1706101)
中医药科技项目(2018ZY03006)
国家自然科学基金项目(81872765)
澳门科学技术发展基金(125/2017/A3)。
关键词
冬虫夏草
肺部疾病
炎症
新药开发
Chinese cordyceps
lung disease
inflammation
drug development
