摘要
目的分析急性缺血性脑梗死(AIS)患者到达医院至静脉溶栓时间(DNT)延长的影响因素。方法79例AIS患者均接受重组人组织型纤溶酶原激活剂(rt-PA)静脉溶栓治疗,根据DNT不同分为延长组(DNT>60 min,n=42)和非延长组(DNT≤60 min,n=37)。对比两组临床资料,分析AIS患者DNT延长的影响因素。结果两组年龄、既往合并心房颤动、TOAST分型为心源性栓塞比较,差异有统计学意义(P<0.05)。与延长组比较,非延长组血压、血糖更低,发病到入院时间、患者及家属溶栓决策时间更短,基线NIHSS评分及HAT评分更高,差异有统计学意义(P<0.05)。结论对于AIS患者,应积极控制影响DNT延长的因素。
Objective To analyze the influencing factors of prolonged door-to-needle time(DNT)in patients with acute ischemic stroke(AIS).Methods A total of 79 patients with AIS received recombinant tissue-type plasminogen activator(rt-PA)intravenous thrombolysis.According to DNT,they were divided into the extended group(DNT>60 min,n=42)and the non-extended group(DNT≤60 min,n=37).The clinical data of the two groups were compared to analyze the influencing factors of DNT prolongation in patients with AIS.Results There were significant differences in age,previous combined atrial fibrillation,and TOAST classification being cardiogenic embolism between the two groups(P<0.05).Compared with the prolonged group,the levels of blood pressure and glucose in the non-prolonged group were lower,time from onset to admission,and thrombolytic decision time were shorter,the baseline NIHSS score and HAT score were higher,the difference was statistically significant(P<0.05).Conclusion For patients with AIS,the factors that affect DNT prolongation should be actively controlled.
作者
陈莉
钟华
CHEN Li;ZHONG Hua(Department of Neurology,People′s Hospital of Nanchuan,Chongqing 408400,China)
出处
《重庆医学》
CAS
2020年第15期2515-2518,共4页
Chongqing medicine
基金
重庆市南川区科技计划项目(2017-4)。
