摘要
目的 对比分析老年性抑郁症患者治疗中应用艾司西酞普兰与帕罗西汀的效果.方法 回顾性分析2016年1月~2017年1月老年性抑郁症患者80例,按照患者治疗中使用的药物不同将其分为观察组、对照组,其中对照组40例接受帕罗西汀治疗,观察组40例患者接受艾司西酞普兰治疗,比较两组临床治疗效果.结果 观察组治疗后总有效率为95%,治疗期间不良反应发生率为7.50%,均优于对照组77.50%、30%(P<0.05);观察组治疗12周后、治疗后1个月SDS评分均低于对照组(P<0.05),观察组治疗后1个月、3个月生活质量评分高于对照组(P<0.05).结论 艾司西酞普兰治疗老年性抑郁症能够较帕罗西汀获得更好的效果,且治疗安全性更高.
Objective To compare and analyze the effect of escitalopram and paroxetine in the treatment of senile depression.Methods A retrospective analysis of 80 patients with senile depression in our hospital from January 2016 to January 2017 was made.According to the different drugs used in the treatment of the patients,they were divided into observation group and control group.40 patients in the control group received paroxetine,40 patients in the observation group received escitalopram,and the clinical effect of the two groups were compared.Results The total effective rate of the observation group was 95%and the incidence of adverse reactions during the treatment was 7.50%,which was better than those of the control group(77.50%and 30%).The SDS scores of the observation group after 12 weeks and 1 month were lower than those of the control group,and the quality of life scores of the observation group after 1 and 3 months were higher than those of the control group(P<0.05).Conclusion Escitalopram is more effective than paroxetine in the treatment of senile depression,and it is more safe and worth popularizing.
作者
冷文君
LENG Wen-jun(Department of Mental Health,Shimen County People’s Hospital,Changde,Hunan 415300,China.)
出处
《中国处方药》
2020年第8期128-130,共3页
Journal of China Prescription Drug
