摘要
目的探讨后颅窝手术后并发尿崩症的原因及诊治措施。方法回顾性分析1例后颅窝术后并发尿崩症患者的临床资料,并复习相关文献。结果通过检测患者术后第1~16 d的尿量、尿比重,并结合其临床症状和体征,诊断为尿崩症。经对症治疗后,患者的尿崩症好转。结论后颅窝手术后并发尿崩症可能的原因是术后脑组织水肿、缺血、血管活性物质刺激,以及麻醉和手术后机体应激反应对抗利尿激素(ADH)产生与释放的暂时性抑制。垂体后叶素或醋酸去氨加压素片的对症治疗和电解质检测及补液是主要的治疗措施。
Objective To explore the causes,diagnosis and treatment of diabetes insipidus after posterior fossa surgery.Methods The clinical data of a patient with postoperative diabetes insipidus after posterior fossa was analyzed retrospectively with literature review.Results By reviewing the urine volume and urine specific gravity from day 1 to day 16 after surgery,combined with clinical manifestations,symptoms and signs,the patient was diagnosed as diabetes insipidus,which was improved after symptomatic treatment.Conclusions Posterior fossa surgery complicated with diabetes insipidus appear to happen due to the restrain of antidiuretic hormone(ADH)generation and release,which is caused by postoperative brain edema,ischemia,stimulation of vascular active substances and response to the body's stress after anesthesia and surgery.Pituitrin or desmopressin acetate,with electrolyte testing and rehydration,are mainly symptomatic treatments.
作者
李顺
晁晓峰
邱娜
战文建
范光伟
梁君
LI Shun;CHAO Xiao-feng;QIU Na(Department of Neurosurgery,the Affiliated Hospital of Xuzhou Medical University,Xuzhou 221000,China)
出处
《临床神经外科杂志》
CAS
2020年第4期445-447,451,共4页
Journal of Clinical Neurosurgery
基金
江苏省研究生科研与实践创新计划项目(SJCX17_0551)。
关键词
后颅窝手术
并发症
尿崩症
诊断
治疗
posterior fossa surgery
complication
diabetes insipidus
diagnosis
treatment
