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重组人促红素联合静脉应用蔗糖铁治疗慢性肾衰竭肾性贫血的临床疗效 被引量:6

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摘要 目的探讨重组人促红素联合静脉应用蔗糖铁治疗慢性肾衰竭肾性贫血的临床疗效。方法选取湖南师范大学附属岳阳医院2017年2月—2018年2月收治的慢性肾衰竭肾性贫血患者124例,采用随机数字表法分为对照组与联合组,各62例。对照组予以重组人促红素注射液治疗,联合组在对照组基础上静脉应用蔗糖铁注射液治疗。两组连续治疗4周。比较两组临床疗效,治疗前后肾性贫血指标〔血清铁蛋白(SF)、血红蛋白(Hb)、转铁蛋白饱和度(TSAT)、血细胞比容(HCT)、血清铁(SI)〕,并观察两组不良反应发生情况。结果联合组临床疗效优于对照组(P<0.05)。治疗前两组两组SF、Hb、TSAT、HCT、SI比较,差异无统计学意义(P>0.05);治疗后联合组SF、Hb、TSAT、HCT、SI高于对照组(P<0.05)。两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论重组人促红素联合静脉应用蔗糖铁治疗慢性肾衰竭肾性贫血的临床疗效确切,可有效改善患者的临床症状和贫血指标,且安全性较高。
作者 易祥明
出处 《临床合理用药杂志》 2020年第21期109-110,共2页 Chinese Journal of Clinical Rational Drug Use
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