摘要
目的:对比增强CT检查中低渗造影剂碘海醇与等渗造影剂碘克沙醇对患者肾功能的影响。方法:回顾性分析2018年3月至2019年12月青海省海西自治州人民医院放射科收治的80例增强CT检查患者病例资料,按照使用造影剂的不同分为观察组与对照组,每组40例,分别采用碘克沙醇与碘海醇,对比两组患者造影前后肾功能、造影效果以及不良反应发生情况。结果:观察组患者造影后Scr、UAER、BUN水平分别为(84.32±6.42)umoL/L、(83.48±10.49)mg/24h、(4.90±1.12)mmoL/L,与对照组比较差异有统计学意义(P<0.05);对比两组患者造影效果结果显示观察组与对照组优良率为95.0%和90.0%,差异无统计学意义(P>0.05);1周后随访患者不良反应率,发现观察组患者有2例出现不良反应,占5.0%,低于对照组的20.0%,有统计学意义(P<0.05)。结论:等渗造影剂碘克沙醇应用于增强CT检查,能够在保证造影效果的基础上,减少对患者肾功能的影响,且不良反应少,值得临床借鉴。
Objective:To compare the effect of iohexol,a hypotonic contrast agent,with iodixanol,an isoosmolar contrast agent,on the renal function of patients.Methods:80 cases of enhanced CT in the radiology department of the People's Hospital of Haixi Autonomous Prefecture from March 2018 to December 2019 were analyzed retrospectively.According to the use of different contrast agents,they were divided into the observation group and the control group,40 cases in each group.The renal function,contrast effect and adverse reactions of the two groups were compared before and after operation.Results:The levels of SCR,UAER and BUN in the observation group were(84.32±6.42)umol/L,(83.48±10.49)mg/24h,(4.90±1.12)mmol/L,respectively,which were significantly different from those in the control group(P<0.05);the contrast results showed that the excellent and good rate in the observation group was 95.0%,in comparison with 90.0%of the other group,and the difference was not statistically significant(P>0.05).The adverse reaction in one week follow-up was found in 2 patients in the observation group,accounting 5.0%,lower than 20.0%in the control group,with statistical significance(P<0.05).Conclusion:The application of icosahol in enhanced CT can reduce the influence on renal function of patients on the basis of ensuring the contrast effect,and has few adverse reactions,which is worthy of clinical reference.
作者
刘勇
领雪峰
陈国章
LIU Yong;LING Xuefeng;CHEN Guozhang(The People's Hospital of Haixi Autonomous Prefecture, Qinghai Delingha 817099, China)
出处
《河北医学》
CAS
2020年第8期1392-1395,共4页
Hebei Medicine
基金
青海省卫生计生系统重点课题项目,(编号:2017-wjzd-01)。
关键词
增强CT
低渗造影剂
碘海醇
等渗造影剂
碘克沙醇
肾功能
Enhanced CT
Hypotonic contrast agent
Iohexol
Isotonic contrast agent
Iodol
Renal function
