摘要
目的比较不同机械通气模式对下腹部外科手术后患者呼吸机相关性膈肌功能障碍的影响。方法选取2017年3月~2019年6月我院ICU收治的接受有创机械通气治疗的下腹部外科手术患者120例作为研究对象,按照通气模式将其分为对照组(n=60)和观察组(n=60),对照组行定压控制通气,观察组行神经调节辅助通气,比较两组ICU入住时间、机械通气时间、治疗后氧化应激指标水平以及人机同步性指标水平。结果观察组ICU入住时间、机械通气时间均短于对照组,差异有统计学意义(P<0.05);观察组超氧化物歧化酶(SOD)、谷胱甘肽(GSH)水平高于对照组,差异有统计学意义(P<0.05);观察组丙二醛(MDA)低于对照组,差异有统计学意义(P<0.05);观察组人机同步性各项评价指标水平均低于对照组,差异有统计学意义(P<0.05)。结论对下腹部外科术后患者行神经调节辅助通气可促使患者人机同步性提升,减少氧化应激反应、ICU入住时间以及机械通气时间,减少呼吸机相关性膈肌功能障碍的发生。
Objective To compare the effects of different mechanical ventilation modes on patients with ventilator-related diaphragmatic dysfunction after lower abdominal surgery.Methods A total of 120 patients undergoing invasive mechanical ventilation in the lower abdomen surgery who were admitted to the ICU of our hospital from March 2017 to June 2019 were selected as the research objects.According to the ventilation mode,they were divided into a control group(n=60)and an observation group(n=60),the control group received constant pressure controlled ventilation,and the observation group received neuromodulation assisted ventilation.The two groups were compared with ICU stay time,mechanical ventilation time,oxidative stress index level after treatment,and man-machine synchronization index level.Results The ICU stay time and mechanical ventilation time of the observation group were shorter than those of the control group,the difference was statistically significant(P<0.05);the levels of superoxide dismutase(SOD)and glutathione(GSH)in the observation group werehigher than the control group,the difference was statistically significant(P<0.05);The malondialdehyde(MDA)of the observation group was lower than that of the control group,the difference was statistically significant(P<0.05);The evaluation index levels were lower than those of the control group,the difference was statistically significant(P<0.05).Conclusion Neuromodulation assisted ventilation for patients after lower abdominal surgery could improve the synchronization of patients and machines,reduce oxidative stress,ICU stay time and mechanical ventilation time,and reduce the occurrence of ventilator-related diaphragm dysfunction.
作者
油文静
朱锋
汪漩
俞洪韵
吕昱
瞿昌晶
YOU Wen-jing;ZHU Feng;WANG Xuan;YU Hong-yun;LV Yu;QU Chang-jing(Department of Critical Care Medicine,Shanghai Yangpu District Central Hospital,Shanghai 200090,China)
出处
《医学信息》
2020年第16期110-111,共2页
Journal of Medical Information
关键词
机械通气
呼吸机相关性膈肌功能障碍
ICU
丙二醛
Mechanical ventilation
Ventilator-related diaphragmatic dysfunction
ICU
Malondialdehyde
