摘要
目的:分析集束化护理对连续性血液净化(CBP)联合低分子肝素治疗重度脓毒症患者的影响。方法:选择2018年1月至2020年4月于我院行CBP联合低分子肝素治疗的重度脓毒症患者62例,按随机数字表法分为两组,各31例。对照组实施常规护理,观察组在常规护理基础上进行集束化护理。比较两组急性生理与慢性健康评分(APACHE-Ⅱ)、临床相关指标及不良事件发生情况。结果:干预前,两组APACHE-Ⅱ评分比较,差异无统计学意义(P>0.05);干预后,观察组APACHE-Ⅱ评分(23.45±4.26)分,低于对照组,差异有统计学意义(P<0.05);观察组置管时间(24.61±6.84)d、住院时间(28.35±7.74)d、治疗费用(1.18±0.56)万元、不良事件发生率3.23%,均低于对照组,差异有统计学意义(P<0.05)。结论:集束化护理有利于加快CBP联合低分子肝素治疗重度脓毒症患者病情恢复,缩短置管时间、住院时间,减少治疗费用及不良事件,值得临床借鉴。
Objective:To analyze the effect of cluster nursing on continuous blood purification(CBP)combined with low molecular weight heparin in patients with severe sepsis.Methods:From January 2018 to April 2020,62 patients with severe sepsis who were treated with CBP combined with low molecular weight heparin in our hospital were divided into two groups according to random digital table method,each.The control group carried out routine nursing,and the observation group carried out cluster nursing on the basis of routine nursing.acute physiological and chronic health scores(APACHE-Ⅱ),clinical related indicators and adverse events were compared between the two groups.Results:Before intervention,two groups APACHE-Ⅱ.There was no significant difference in II score(P>0.05).After intervention,the APACHE-Ⅱ(23.45±4.26)score in the observation group was lower than that in the control group(P<0.05).The time of catheterization(24.61±6.84)d,the time of hospitalization(28.35±7.74)d,the cost of treatment(1.18±0.56)yuan and the incidence of adverse events in the observation group were lower than those in the control group(3.23%),the difference was statistically significant(P<0.05).Conclusion:Cluster nursing can accelerate the CBP combined with low molecular weight heparin treatment of severe sepsis patients recovery,shorten the time of catheterization,hospital stay,reduce treatment costs and adverse events,worthy of application.
作者
赵艳敏
朱藏花
孙雪真
栾自红
ZHAO Yan-min;ZHU Zang-hua;SUN Xue-zhen;LUAN Zi-hong(General ICU of the First Affiliated Hospital of Zhengzhou University,Zhengzhou Henan 450000,China;Laboratory Department,First Affiliated Hospital of Zhengzhou University,Zhengzhou Henan 450000,China)
出处
《药品评价》
CAS
2020年第9期43-45,共3页
Drug Evaluation
关键词
脓毒症
集束化护理
连续性血液净化
低分子肝素
Sepsis
Cluster Care
Continuous Blood Purification
Low Molecular Weight Heparin
