摘要
血管内皮细胞具有内分泌功能,该功能受损是高血压、动脉粥样硬化的始动因素,也是胰岛素抵抗、β细胞功能受损、糖尿病及其并发症发生的病理基础。认识血管功能的异常、探索其发病机理对有效预防糖尿病血管并发症、提高患者生存率及生活质量十分重要。文章综述了血管内皮细胞功能与糖尿病关系的研究进展。
Vascular endothelial cells have endocrine function,and the impaired function is not only the initial factor of hypertension and atherosclerosis,but also the pathological basis of insulin resistance,impairedβ-cell function,diabetes and its complications.Understanding the abnormality of vascular function and exploring its pathogenesis is very important to effectively prevent vascular complications of diabetes and improve the survival rate and quality of life of patients.
作者
高雁鸿
刘建志
王仁山
张年萍
GAO Yan-hong;LIU Jian-zhi;WANG Ren-shan;ZHANG Nian-ping(Department of Endocrinology,The Fifth People's Hospital of Datong,Datong Shanxi,030009;The First Affiliated Hospital,Datong Shanxi,030009;Datong Yuncheng Endocrine Hospital,Datong Shanxi,037006;Department of Internal Medicine,Datong Xinjiankang Hospital,Datong Shanxi,037036;School of Medicine,Shanxi Datong University,Datong Shanxi,037009)
出处
《山西大同大学学报（自然科学版）》
2020年第4期50-54,66,共6页
Journal of Shanxi Datong University(Natural Science Edition)
关键词
内皮细胞
胰岛素抵抗
Β细胞功能
糖尿病
endothelial cells
insulin resistance
β-cell function
diabetes mellitus
