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不同硬膜外麻醉给药方案对足月初产妇分娩疼痛、麻醉药用量及不良反应的影响 被引量:1

Effects of Different Epidural Anesthesia Regimens on Labor Pain,Anesthetic Dosage and Adverse Reactions in Full-Term-Delivery Primiparas
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摘要 目的探讨不同硬膜外麻醉给药方案对足月初产妇分娩疼痛、麻醉药用量及不良反应的影响。方法选取拟接受硬膜外麻醉镇痛的足月初产妇105例,按随机数字表法分为2组:对照组52例,予以硬膜外持续给药方案;观察组53例,予以硬膜外规律间断给药方案。比较2组分娩时疼痛程度(VAS评分)、麻醉药物用量及不良反应情况。结果与麻醉镇痛前比较,2组硬膜外麻醉镇痛后各时间节点(镇痛后2 h、镇痛后3 h、分娩时及分娩后1 h)VAS评分均显著降低,差异有统计学意义(均P<0.05);与对照组比较,观察组镇痛后各时间节点(镇痛后3 h、分娩时及分娩后1 h)VAS评分、麻醉药物(舒芬太尼、罗哌卡因)用量、不良反应(发热)发生率均显著降低,差异有统计学意义(均P<0.05)。结论硬膜外麻醉镇痛时采取规律间断给药方案能显著改善足月初产妇镇痛效果,减少药物用量,降低常见发热现象的发生率,安全性较高。 Objective To analyze the effects of different epidural anesthesia regimens on labor pain,anesthetic dosage and adverse reactions in full-term-delivery primiparas.Methods A total of 105 full-term-delivery primiparas were randomly assigned to receive either continuous epidural administration(control group,n=52)or regular intermittent epidural administration(observation group,n=52).Labor pain(VAS score),anesthetic dosage and adverse reactions were compared between the two groups.Results The VAS scores significantly decreased in both groups at 2 h after analgesia,3 h after analgesia,delivery and 1 h after delivery(P<0.05).Compared with control group,VAS scores,dosages of sufentanil and ropivacaine and incidence of fever markedly decreased in observation group(P<0.05).Conclusion The regular intermittent epidural administration regimen can effectively and safely improve analgesic effect and reduce anesthetic dosage and incidence of fever in full-term-delivery primiparas.
作者 郑丽宾 ZHENG Li-bin(Department of Anesthesiology,Zhengzhou Bridge Hospital,Zhengzhou 450000,China)
出处 《实用临床医学(江西)》 CAS 2020年第6期22-24,共3页 Practical Clinical Medicine
关键词 硬膜外麻醉 初产妇 分娩 麻醉用药量 不良反应 给药方案 epidural anesthesia primipara delivery anesthetic dosage adverse reactions administration regimen
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