摘要
[目的]系统评价电针夹脊穴疗法与单纯西药治疗带状疱疹的疗效及安全性,为带状疱疹治疗提供准确的临床决策。[方法]在中国知网(CNKI)、万方(Wanfang)、维普(VIP)、中国生物医学文献数据库(CBM)、Web of Science、EMbase、PubMed、Cochrane Library及相关注册平台检索有关电针夹脊穴治疗带状疱疹的随机对照实验研究(RCT)文献,并使用RevMan 5.3进行Meta分析,以GRADE系统对证据质量进行分级。[结果]研究涉及1 758例病人参与的23个RCTs。Meta分析显示,电针夹脊穴疗法在有效率[RR=1.22,95%CI(1.15,1.30)]、视觉模拟评分(VAS)[MD=1.93,95%CI(1.64,2.23)]、临床症状评分[MD=1.21,95%CI(1.03,1.38)]方面与西药组比较总体差异均有统计学意义(P<0.001)。GRADE系统证据质量分级显示质量较低。[结论]现有证据表明,电针夹脊穴及其联合其他疗法治疗带状疱疹疗效优于单纯西药治疗,但证据质量级别仍属较低水平,故需要更严格的设计、大规模的RCT确认电针夹脊穴疗法治疗带状疱疹的疗效。
Objective:To systematically evaluate the efficacy and safety of electroacupuncture at Jiaji points and single western medicine for herpes zoster,so as to provide accurate clinical decision-making for the treatment of herpes zoster.Methods:Literatures on randomized controlled trials(RCTs)about the treatment of herpes zoster using electroacupuncture at Jiaji points were retrieved from the CNKI,Wanfang,VIP,CBM,Web of Science,EMbase,PubMed,Cochrane Library and related registration platforms. Meta-analysis was carried out by using Sofeware RevMan 5. 3. And quality of evidence was graded,according to GRADE system.Result:Totally 23 RCTs were included in this study,involving 1 758 patients. Meta-analysis showed that there were statistical differences(P<0. 001)on total efficacy[RR=1. 22,95%CI(1. 15,1. 30)],Visual Analogue Scale(VAS)[MD=1. 93,95%CI(1. 64,2. 23)],and clinical symptoms score[MD=1. 21,95%CI(1. 03,1. 38)]between electroacupuncture at Jiaji points and western medicine. However,GRADE system showed that the quality of evidence was at a lower level.Conclusion:Existing evidence shows that the efficacy of electroacupuncture at Jiaji points combined with other therapies could be more better than that of single western medicine for the treatment of herpes zoster. But the quality of evidence is still at a lower level. Therefore,RCTs with more rigorous design and more large scale shoule be conducted,in order to confirm the therapeutic effect of electroacupuncture at jiaji points on herpes zoster.
作者
银子涵
张琼月
徐桂兴
付亚男
陈姣
赵凌
梁繁荣
YIN Zihan;ZHANG Qiongyue;XU Guixing;FU Yanan;CHEN Jiao;ZHAO Ling;LIANG Fanrong(School of Acu-mox and Tuina,Chengdu University of TCM,Sichuan 610075 China)
出处
《护理研究》
北大核心
2020年第16期2809-2819,共11页
Chinese Nursing Research
基金
国家自然科学基金委员会资助项目——重大项目,编号:81590950。
关键词
带状疱疹
电针
夹脊穴
系统评价
Meta分析
GRADE分级
疗效
安全性
herpes zoster
electroacupuncture
Jiaji points
systematic review
meta-analysis
grading of recommendations assessment
development and evaluations(GRADE)
efficacy
safety
