摘要
目的:探讨颅内高分辨率磁共振(HRMRI)诊断症状性颅内动脉狭窄的临床价值。方法:以2018年1月~2019年1月某院神经内科收治的60例MRA或CTA提示颅内动脉狭窄的急性脑梗死患者为研究对象,随机分为对照组和实验组各30例。对照组患者常规脑梗死治疗,实验组患者在对照组基础上加用HRMRI诊断及治疗颅内动脉狭窄,观察实验组HRMRI诊断结果以及两组随访预后。结果:实验组HRMRI诊断28例动脉狭窄为动脉硬化斑块所致,包括稳定型斑块17例,不稳定型斑块11例,其中复杂斑块2例,另管壁发育不良1例、血管炎1例。基于HRMRI诊断治疗,实验组随访1年复发率(3.3%)与病死率(0%)均低于对照组,差异有统计学意义(P<0.05)。结论:HRMRI可以有效检出颅内动脉狭窄、明确病因及定性斑块,能够为临床诊治提供有价值的影像学参考,值得使用及推广。
Objective:To investigate the clinical value of high resolution intracranial magnetic resonance imaging(HRMRI)in the diagnosis of symptomatic intracranial artery stenosis.Methods:60 acute cerebral infarction patients with intracranial artery stenosis indicated by MRA or CTA admitted to the department of neurology of a hospital from January 2018 to January 2019 were randomly divided into two groups,with 30 cases in each group.The control group was given conventional cerebral infarction treatment,and the experimental group were diagnosed and treated with HRMRI on the basis of the control group.The HRMRI diagnosis results of the experimental group and the follow-up prognosis of the two groups were observed.Results:In the experimental group,28 cases of arterial stenosis were caused by arteriosclerosis plaque diagnosed by HRMRI,including 17 cases of stable plaque,11 cases of unstable plaque,and including 2 cases of complex plaque.There was another 1 case of vascular wall dysplasia,and 1 case of vasculitis in the experimental group.Based on HRMRI diagnosis and treatment,the recurrence rate(3.3%)and mortality rate(0%)of the experimental group were lower than those of the control group in one year of follow-up,with statistically significant differences(P<0.05).Conclusion:HRMRI can effectively detect intracranial artery stenosis,identify the cause and qualitative plaque,and provide valuable imaging reference for clinical diagnosis and treatment,which is worthy of promotion and application.
作者
许冬华
闵志刚
任占云
施俊峰
徐龙
Xu Donghua;Min Zhigang;Ren Zhanyun;Shi Junfeng;Xu Long(Department of Neurology,Yixing People's Hospital,Yixing 214200;Department of Medical Imaging,Yixing People's Hospital,Yixing 214200)
出处
《数理医药学杂志》
2020年第9期1273-1274,共2页
Journal of Mathematical Medicine
基金
无锡市科技发展医疗卫生项目指导性计划项目资助(项目编号WX03-02B0105-071800-81)
