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分析中药炮制质量对药物不良反应及药效的影响 被引量:5

Analysis of the influence of processing quality of traditional Chinese medicine on adverse drug reactions and efficacy
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摘要 目的探讨中药炮制质量对药物不良反应及药效的影响。方法选择沈阳市第二中医院2018年1月至2019年3月应用中药治疗的200例患者作为研究对象,按照随机数字表法分为对照组与观察组,各100例。对照组患者使用的中药未经规范化炮制处理,观察组患者使用的中药经规范化炮制处理,比较两组临床疗效、不良反应发生率、生活质量评分、满意度。结果观察组临床总有效率为97.00%,高于对照组的86.00%(P<0.05)。观察组不良反应发生率为5.00%,低于对照组的15.00%(P<0.05)。治疗后,两组生活质量评分均较治疗前增加,且观察组生活质量评分高于对照组(P<0.05)。观察组总满意率为95.00%,高于对照组的82.00%(P<0.05)。结论中药经规范化炮制后可提高中药的药效,减少不良反应,有利于提升患者生活质量和满意度。 Objective To investigate the effect of processing quality of traditional Chinese medicine on adverse drug reactions and efficacy.Methods 200 cases of patients treated in Shenyang Second Hospital of Traditional Chinese Medicine from January 2018 to March 2019 were selected as the research objects,and they were randomly divided into control group and observation group,with 100 cases in each group.The traditional Chinese medicine used by the patients in the control group was not standardized,while the traditional Chinese medicine used by the patients in the observation group was treated with standardized processing.The clinical efficacy,incidence of adverse reactions,quality of life score and satisfaction were compared between the two groups.Results The total effective rate of the observation group was 97.00%,which was higher than 86.00%of the control group(P<0.05).The incidence of adverse reactions in the observation group was 5.00%,which was lower than 15.00%in the control group(P<0.05).After treatment,the quality of life scores of the two groups were increased compared with before treatment,and the quality of life score of the observation group was higher than that of the control group(P<0.05).The total satisfaction rate of the observation group was 95.00%,which was higher than 82.00%of the control group(P<0.05).Conclusion Standardized processing of traditional Chinese medicine can improve the efficacy of traditional Chinese medicine,reduce adverse reactions,and improve the quality of life and satisfaction of patients.
作者 赵洪超 关书博 王丹 Zhao Hongchao;Guan Shubo;Wang Dan(Department of Pharmacy,Shenyang Second Hospital of Traditional Chinese Medicine,Shenyang,Liaoning,110101,China)
出处 《当代医学》 2020年第27期103-105,共3页 Contemporary Medicine
关键词 中药 炮制 不良反应 药效 Traditional Chinese medicine Processing Adverse reactions Efficacy
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