摘要
由于肥胖的流行和相关疾病的发生率不断增长,各学术组织纷纷制定控制肥胖的指南与共识,均将减少热卡摄入作为肥胖管理的基础。但是,饮食管理的方式多样,共识中并没有推荐具体的饮食方案。究竟是采取持续禁食方案还是间歇禁食(IMF)方案,一直是大家关注的问题。最近,《新英格兰医学杂志》发表了有关间歇禁食的重要综述,总结人类近20年来对间歇禁食的认识,系统地介绍间歇禁食在动物实验和人类研究的结果,提供了间歇禁食有助于延长寿命、使代谢获益、保护器官等的有力证据。本文结合以往研究结果,阐述间歇禁食的益处、可能机制及存在的挑战和任务。
As the obesity epidemic and related diseases increase,various academic organizations have formulated guidelines and consensus on relevant control notices,all of which regard the reduction of calorie intake as the basis of obesity management.However,there are various ways of diet management,and no specific diet management plan is recommended in the consensus.Most guidelines recommend a continuous energy restriction,but patients have poor adherence and rebound after short-term weight loss.It is a question of whether intermittent fasting is better than continuous energy restriction.Recently,the New England Journal of Medicine published an important review of intermittent dieting,which summarized the understanding of intermittent dieting in the past 20 years,and systematically introduced the strong evidence of extended life,metabolic benefits and organ protection of intermittent diet in animal experiments and human studies.
作者
高鑫
GAO Xin(Department of Endocrinology and Metabolism, Zhongshan Hospital, Fudan University, Shanghai 200032, China)
出处
《中国临床医学》
2020年第4期535-539,共5页
Chinese Journal of Clinical Medicine
关键词
肥胖
间歇禁食
慢性病
机制
obesity
intermittent fasting
chronic disease
mechanism
