摘要
目的:分析住院儿童感染革兰阴性菌情况及耐药性。方法:选取120例住院患儿作为研究对象,收集痰液进行细菌培养、鉴定,计算革兰阴性菌检出率,并对检出革兰阴性菌进行药敏试验以分析耐药性。结果:120例患儿收集标本120份,经细菌培养后检出73株革兰阴性菌,检出率为60.83%(73/120),其中以大肠埃希菌、肺炎克雷伯菌肺炎亚种、阴沟肠杆菌最常见。采用药敏试验对73株革兰阴性菌耐药情况进行分析显示,革兰阴性菌对阿莫西林耐药率最高为28.77%,对亚胺培南耐药率最低为2.74%。结论:分析住院患儿感染革兰阴性菌情况及耐药情况对临床治疗具有积极意义,能提升抗生素使用效果。
Objective:To analyze the situation of Gram-negative bacteria infection and drug resistance in hospitalized children.Method:A total of 120 hospitalized children as the research object,the sputum was collected for bacterial culture and identification,the detection rate of Gram-negative bacteria was calculated,and the drug sensitivity test of Gram-negative bacteria was carried out to analyze the drug resistance.Result:A total of 120 samples were collected from 120 children,and 73 strains of Gram-negative bacteria were detected after bacterial culture,and the detection rate was 60.83%(73/120).Among them,the most common bacteria included Escherichia Coli,Klebsiella Pneumoniae Subspecies and Enterobacter Cloacae.Drug sensitivity test was used to analyze the drug resistance of 73 strains of Gram-negative bacteria,and the results showed that the highest resistance rate of Gram-negative bacteria to Amoxicillin was 28.77%,and the lowest resistance rate to Imipenem was 2.74%.Conclusion:The analysis of Gram-negative bacteria infection and drug resistance in hospitalized children has positive significance for clinical treatment and can improve the effect of antibiotic use.
作者
吴会利
饶庆通
WU Huili;RAO Qingtong(Dabu County People’s Hospital,Dabu 514299,China;不详)
出处
《中外医学研究》
2020年第24期163-164,共2页
CHINESE AND FOREIGN MEDICAL RESEARCH
基金
梅州市科技计划项目(2018B142)。
关键词
住院儿童
革兰阴性菌
耐药性
Children in hospital
Gram-negative bacteria
Drug resistance
