摘要
目的:探讨不同检测方法在宫颈癌筛查中的诊断效能差异。方法:选取漳州正兴医院2017年1月-2019年2月收治的宫颈病变患者196例为研究对象。对患者进行HPV-DNA检测和TCT检测,并将两种检测结果及联合检测结果与病理组织学检验结果进行比较研究。比较不同检测方法的灵敏度、特异度和诊断符合率。结果:联合检测的特异度和诊断符合率(99.32%、97.45%)均高于HPV-DNA检测(89.04%、91.33%)及TCT检测(91.10%、91.33%),差异有统计学意义(P<0.05);HPV-DNA检测的灵敏度高于TCT检测及联合检测,但差异无统计学意义(P>0.05)。结论:采用HPV-DNA联合TCT检测方法进行宫颈癌诊断具有较高的特异度,能够提升临床诊断的准确率,是临床宫颈癌筛查的理想方式之一。
Objective:To investigate the difference of diagnostic efficacy between different detection methods in cervical cancer screening.Method:From January 2017 to February 2019,196 patients with cervical lesions admitted in Zhengxing Hospital of Zhangzhou were selected as the study objects.The patients were detected by HPV-DNA and TCT.The results of the two kinds of detection and combined detection were compared with the results of histopathology.The sensitivity,specificity and diagnostic coincidence rate of different detection methods were compared.Result:The specificity and diagnostic coincidence rate of combined detection(99.32%,97.45%)were higher than those of HPV-DNA detection(89.04%,91.33%)and TCT detection(91.10%,91.33%),and the differences were statistically significant(P<0.05).The sensitivity of HPV-DNA detection was higher than that of TCT detection and combined detection,but the difference was not statistically significant(P>0.05).Conclusion:HPV-DNA combined with TCT has high specificity in the diagnosis of cervical cancer,which can improve the accuracy of clinical diagnosis,and it is one of the ideal methods for clinical cervical cancer screening.
作者
赖巧凤
LAI Qiaofeng(Zhengxing Hospital of Zhangzhou,Zhangzhou 363000,China)
出处
《中外医学研究》
2020年第22期86-88,共3页
CHINESE AND FOREIGN MEDICAL RESEARCH
