摘要
目的:探讨喷他佐辛维持麻醉对全麻不孕症患者腹腔镜手术术后镇痛及性激素水平的影响。方法:选取2018年8月—2019年7月本院收治的输卵管性不孕症行腹腔镜手术患者104例,随机分为对照组、观察组各52例。两组均给予丙泊酚+瑞芬太尼+顺式苯磺酸阿曲库铵静脉全麻,于手术结束前30 min对照组静脉注射芬太尼,观察组静脉注射喷他佐辛。比较两组PHPS疼痛评分、ramsay镇静评分、性激素水平、不良反应。结果:两组患者术后T1、T2、T3、T4、T5时刻疼痛评分及镇静评分比较均无差异(P>0.05);卵泡刺激素(FSH)、黄体生成素(LH)、雌二醇(E2)水平均高于术前(P<0.05),但两组间术前、术后比较无差异(P>0.05);不良反应发生率对照组(19.2%)高于观察组(5.8%)(P<0.05)。结论:喷他佐辛维持麻醉对全麻不孕症患者腹腔镜手术术后镇痛效果确切,术后不良反应发生率更低,且对患者术后性激素水平的影响未见变化。
Objective:To investigate the influence of pentazocine maintenance anesthesia on the postoperative analgesia and sex hormone levels of patients after laparoscopic surgery under general anesthesia.Methods:104 patients with tubal infertility who had experienced laparoscopic surgery were enrolled and were randomly divided into two groups(52 cases in each group)from August 2018 to July 2019.All patients had received propofol combined with remifentanil and cisatracurium besilate for general anesthesia.30 minutes before the end of the operation,the patients in the control group were given fentanyl injected intravenously,and the patients in the observation group were given patazoxin injected intravenously.The Prince Henry Pain Score(PHPS),ramsay sedation score,sex hormone levels,and the rate of adverse reaction of the patients were compared between the two groups.Results:There were no significant different in the PHPS and the ramsay sedation score at postoperative T1,T2,T3,T4,and T5 of the patients between the two groups(P>0.05).After operation,the levels of FSH,LH,and E2 of the patients in the two groups had increased significantly(P<0.05),but which had no significant different before and after operation between the two groups(P>0.05).The incidence of adverse reaction of the patients in the control group was 19.2%,which was significant higher than that(5.8%)of the patients in the observation group(P<0.05).Conclusion:Pentazocine maintenance anesthesia for treating infertility patients after laparoscopic surgery under general anesthesia has definite analgesic effect,which has lower incidence of postoperative adverse reactions,and has the same influence on the sex hormone levels of patients when compared to those of fentanyl.
作者
马双成
黎静
王慧
MA Shuangcheng;LI Jing;WANG Hui(Shuangliu District Maternal and Child Health Care Hospital of Chengdu, Sichuan Province, 610200)
出处
《中国计划生育学杂志》
2020年第8期1230-1233,共4页
Chinese Journal of Family Planning
关键词
不孕症
腹腔镜手术:喷他佐辛
维持麻醉
镇痛:镇静
不良反应
性激素
Infertility
Laparoscopic surgery
Pentazocine
Maintenance anesthesia
Analgesia
Sedation
Adverse reactions
Sex hormone
