摘要
为探讨吖啶橙N壬基修饰对其紫外光谱和荧光光谱的影响,并为筛选不同细胞通透性的荧光染料提供依据,本文以吖啶橙为原料,通过氮壬基化,合成了N-壬基吖啶橙碘化物(NAO),并对其结构进行了表征。p H对N-壬基吖啶橙荧光光谱的影响较大,p H=7.45时的荧光强度最大。吖啶橙壬基化基本保持了母体优异的荧光特性。
In order to explore the influence of acridine orange nonylation on its UV and fluorescence spectra,and provide the basis for screening different cell permeability fluorescent dyes,N-nonyl acridine orange was synthesized from acridine orange with 1-Iodononane.N-nonylacridine orange had strong characteristic absorption at 496nm.Fluorescence spectrum indicated that pH had a significant influence on the fluorescence spectrum of n-nonylacridine orange,and the fluorescence intensity was the highest when pH=7.45.N-nonylacridine orange maintained the excellent fluorescence characteristics of their parent.
作者
冯志明
伍斌
冯振南
FENG Zhiming;WU Bing;FENG Zhengnan(College of Chemistry and Chemical Engineering,Hunan Normao University,Changsha 410081,China;Hainan Medical University,Haikou 570102,China)
出处
《化工技术与开发》
CAS
2020年第9期17-18,共2页
Technology & Development of Chemical Industry
关键词
壬基吖啶橙
合成
光谱性质
N-nonylacridine orange
synthesis
spectral property
