摘要
目的探究分析丙基硫氧嘧啶联合甲状腺片治疗甲状腺功能亢进症的临床疗效。方法选取我院在2018年1月至2019年1月时间段内收治的甲状腺功能亢进症患者87例,以治疗时间先后顺序进行分组,42例为对照组,剩余45例为探究组,针对两组患者分别给予单一甲状腺片治疗与丙基硫氧嘧啶联合甲状腺片治疗,对两组患者治疗前后的生活质量情况、临床疗效及治疗后不良反应率予以比较分析。结果组间比较显示,治疗前两组患者生活质量评分并无明显差异(P> 0.05);治疗后探究组患者的生活质量评分显著高于对照组(P <0.05);且探究组患者的临床疗效亦明显优于对照组(P <0.05);就治疗后不良反应率而言,探究组患者明显低于对照组(P <0.05)。结论在甲状腺功能亢进症患者治疗期间实施丙基硫氧嘧啶联合甲状腺片治疗可达理想效果,其可在保障临床疗效的基础上降低治疗后不良反应发生概率,保障治疗安全性,同时提高患者治疗后的生活质量,故可于临床中进一步推广、运用。
Objective To explore and analyze the clinical effi cacy of propylthiouracil combined with thyroid tablets in the treatment of hyperthyroidism.Methods From January 2018 to January 2019,87 patients with hyperthyroidism were treated in our hospital,42 patients were divided into control group and the remaining 45 patients were in the inquiry group.They were treated with single thyroid tablets and propylthiouracil combined with thyroid tablets respectively.The quality of life,clinical effi cacy and adverse reactions of the two groups before and after treatment were evaluated,compared and analyzed.Results There was no signifi cant diff erence in the quality of life score between the two groups before treatment(P>0.05);after treatment,the quality of life score of the inquiry group was signifi cantly higher than that of the control group(P<0.05);and the clinical efficacy of the inquiry group was also significantly better than that of the control group(P<0.05);in terms of the rate of adverse reactions after treatment,the inquiry group was signifi cantly lower than that of the control group(P<0.05).Conclusion The ideal effect of propylthiouracil combined with thyroid tablets in the treatment of hyperthyroidism patients can be achieved.It can reduce the incidence of adverse reactions after treatment,ensure the safety of treatment and improve the quality of life of patients after treatment,so it can be further promoted and applied in clinic.
作者
王铮宇
WANG Zhengyu(Department of Endocrinology,Xinmin People's Hospital,Xinmin 110300,China)
出处
《中国医药指南》
2020年第24期133-134,共2页
Guide of China Medicine
