摘要
目的观察患者胆囊息肉的动态变化并分析胆囊息肉发生的危险因素。方法回顾性分析2014年1月至2017年12月在宣武医院健康筛查中心接受腹部超声体检者的相关资料,动态观察胆囊息肉变化情况,对其中多次体检均有胆囊息肉(息肉组,n=1149)人群与多次体检均未发现胆囊息肉的(对照组,n=18243)人群,及息肉发生及与消失情况进行对比分析。结果息肉组占比(n=1149,52.1%)>新发组(n=797,36.2%)>消失组(n=258,11.7%)。胆囊息肉在中年人群中占比最大;息肉新发人群集中在30.0~59.0岁,而胆囊息肉消失的顶峰在60岁以后。息肉组与对照组在年龄、男性、血糖、总胆固醇、低密度脂蛋白、舒张压方面差异均有统计学意义(均P<0.05)。多因素分析显示,年龄(OR=1.152)、男性(OR=1.407)及低密度脂蛋白(OR=1.656)是胆囊息肉形成的独立危险因素。结论胆囊息肉的年发病率为9.7‰,多见于中年,且发病率在升高;胆囊息肉可自行消失,但随着胆囊息肉初始直径的增大,消失概率减小。年龄、男性、低密度脂蛋白升高为胆囊息肉形成的独立危险因素。
Objective To study the occurrence and disappearance of gallbladder polyps in patients who underwent multiple ultrasonographic examinations,and to determine the risk factors of formation of gallbladder polyps.Methods From January 2014 to December 2017,relevant data on patients who underwent follow-up abdominal ultrasound examinations at the Health Screening Center of Xuanwu Hospital was retrospectively analyzed,and the dynamic changes of gallbladder polyps were assessed.A comparative analysis was then conducted between those who had gallbladder polyps(the gallbladder polyps group,n=1149)and those who had no gallbladder polyps(the control group,n=18243).The occurrence,changes and disappearance of gallbladder polyps shown on multiple untrasonographic examinations were compared.Results The patterns of changes of gallbladder polyps showed that the proportions of patients with gallbladder polyps which were stable in size(n=1149,52.1%)were greater than those who had new appearance of gallbladder polyps(n=797,36.2%),and these 2 groups of patients were having higher proportions than those who had disappearance of gallbladder polyps(n=258,11.7%).The largest proportion of gallbladder polyps were found in middle-aged people,and new polyps were mainly found in the age group of 30.0-59.0 years.The peak of gallbladder polyps incidence was after age 60.There were significant differences in age,male,blood glucose,total cholesterol,low density lipoprotein(LDL),and diastolic blood pressure between the study and the control groups(all P<0.05).Multivariate analysis showed that age(OR=1.152),male(OR=1.407)and LDL(OR=1.656)were independent risk factors of gallbladder polyp formation.Conclusions The annual incidence of gallbladder polyps was 9.7‰.Gallbladder polyps were more commonly found in middle age,and the incidence of gallbladder polyps was increasing.Gallbladder polyps could disappear.However,with increase in initial diameter of gallbladder polyps,the probability of disappearance decreased.Age,male gender and elevated LDL were independent risk factors of gallbladder polyps formation.
作者
姚贵宾
刘力玮
白雪松
周震
黄跃
郑亚民
Yao Guibin;Liu Liwei;Bai Xuesong;Zhou Zhen;Huang Yue;Zheng Yamin(Department of General Surgery,Xuanwu Hospital,Capital Medical University,Beijing 100053,China;The First Clinical College,Xuanwu Hospital,Capital Medical University,Beijing 100053,China;The Biomedical Engineering College,Beijing 100069,China;Information Centre of Xuanwu Hospital,Capital Medical University,Beijing 100053,China)
出处
《中华肝胆外科杂志》
CAS
CSCD
北大核心
2020年第8期606-610,共5页
Chinese Journal of Hepatobiliary Surgery
关键词
胆囊疾病
胆囊息肉
危险因素
超声
随访观察
Gallbladder diseases
Gallbladder polyps
Risk factors
Ultrasound
Follow-up observation
