摘要
目的探讨瓜蒌宽肠胶囊联合电针干预对腹部手术后胃肠功能恢复的影响。方法选取医院2017年1月至2019年1月行腹部手术的患者120例,按随机数字表法分为对照组和观察组,各60例。两组患者术后均予禁食禁饮、抗感染、调节电解质平衡、监测生命体征、补充营养等常规处理,并予电针干预;观察组患者加服瓜蒌宽肠胶囊。两组均治疗3 d。结果观察组总有效率为98.33%,显著高于对照组的85.00%(P<0.05);治疗后,观察组患者术后的肠鸣音恢复时间、首次排气时间、通便时间均显著短于对照组,胃泌素、生长抑素、胃动素水平均显著高于对照组,白细胞介素6和C反应蛋白水平均显著低于对照组(P<0.05)。两组均未发现不良反应/不良事件。结论腹部手术后应用瓜蒌宽肠胶囊联合电针进行干预,能显著促进患者术后胃肠功能恢复,改善胃肠激素水平,降低相关炎性因子水平。
Objective To explore the effect of Gualou Kuanchang Capsules combined with electro-acupuncture intervention on the recovery of gastrointestinal function after abdominal surgery.Methods A total of 120 patients who underwent abdominal surgery from January 2017 to January 2019 in the hospital were selected and divided into the control group and observation group according to random number table method,60 cases in each group.Both groups given conventional treatments such as fasting,anti-infection,regulating electrolyte balance,monitoring vital signs,and supplementing nutrition,and were given electro-acupuncture intervention,while the observation group was added with Gualou Kuanchang Capsules.Both groups were treated for 3 d.Results The total effective rate of the observation group was 98.33%,which was significantly higher than 85.00%of the control group(P<0.05).After treatment,the postoperative bowel sound recovery time,first exhaust time,and laxative time of the observation group were significantly shorter than those of the control group;the levels of gastrin,somatostatin,and motilin were significantly higher than those of the control group;the levels of interleukin-6(IL-6)and C-reactive protein were significantly lower than those of the control group(P<0.05).No adverse drug reactions/adverse events were found in both groups.Conclusion The application of Gualou Kuanchang Capsules combined with electro-acupuncture after abdominal surgery can significantly promote the recovery of gastrointestinal function,improve the level of gastrointestinal hormones,and reduce the level of related inflammatory factors.
作者
李明珠
彭丽艳
王春艳
李娟
王慧丽
LI Mingzhu;PENG Liyan;WANG Chunyan;LI Juan;WANG Huili(Tangshan Maternal and Child Health Hospital,Tangshan,Hebei,China 063000)
出处
《中国药业》
CAS
2020年第18期63-65,共3页
China Pharmaceuticals
基金
河北省中医药管理局科研计划项目[2019207]。
关键词
瓜蒌宽肠胶囊
电针
腹部手术
胃肠功能
临床疗效
Gualou Kuanchang Capsules
electro-acupuncture
abdominal surgery
gastrointestinal function
clinical efficacy
