摘要
目的对重症肺炎合并糖尿病患者的预后影响因素进行分析。方法选取我院呼吸科2018年3月—2019年3月确诊为重症肺炎合并糖尿病共100例展开研究,根据患者的预后情况将患者分为观察组及对照组,对两组患者的预后影响因素及并发症情况进行分析。结果观察组患者性别、住院时间差异无统计学意义(P>0.05),患者的抗生素的应用、血糖水平,脓血症与对照组比较,差异具有统计学意义(P<0.05)。对比两组患者的血清炎性因子可见,观察组患者的IL-6、TNF-α、CRP、PCT水平低于对照组,组间差异具有统计学意义(P<0.05)。将死亡结果为因变量,将年龄、抗生素的使用、血糖水平、脓毒血症、IL-6、TNF-α、CRP、PCT水平纳入Logistic多因素回归方程,结果显示,相关性因素为血糖水平、脓毒血症、抗生素的使用IL-6、TNF-α、CRP、PCT。结论通过对重症肺炎合并糖尿病预后影响因素进行分析可见,患者的年龄、血糖控制状况、脓血症、抗生素的使用、炎性因子水平等均为影响预后的关键因素,其数据水平具有临床预测指导价值。
Objective To analyze the prognostic factors of severe pneumonia with diabetes mellitus.Methods A total of 100 patients diagnosed with severe pneumonia and diabetes mellitus in the respiratory department of our hospital from March 2018 to March 2019 were selected for the study.The patients were divided into the observation group and the control group according to the prognosis of the patients,and the prognostic factors and complications of the patients in the two groups were analyzed.Results There was no significant difference in gender and length of stay in the observation group(P>0.05),there were statistically significant differences in antibiotic use,blood glucose level,and abscess between the two groups(P<0.05).Compared with the serum inflammatory factors of the two groups,the levels of IL-6,TNF-α,CRP and PCT in the observation group were lower than those in the control group,and the difference between the two groups was statistically significant(P<0.05).Taking the death results as dependent variables,age,antibiotic use,blood glucose level,sepsis,IL-6,TNF-α,CRP,PCT levels were included in the logistic multiple factor regression equation.The results showed that the correlation factors were blood glucose level,sepsis,antibiotic use,IL-6,TNF-α,CRP,PCT.Conclusion Through the analysis of the prognostic factors of severe pneumonia complicated with diabetes,we can see that the age of patients,blood glucose control status,abscess,the use of antibiotics,the level of inflammatory factors are the key factors affecting the prognosis,and the data level has clinical predictive value.
作者
阮剑铠
谢海燕
陈方榕
佘晖
RUAN Jiankai;XIE Haiyan;CHEN Fangrong;SHE Hui(Department of Respiratory and Critical Care Medicine,Fuzhou Second Hospital of Xiamen University,Fuzhou Fujian 350000,China)
出处
《中国卫生标准管理》
2020年第17期50-52,共3页
China Health Standard Management
关键词
重症肺炎
合并糖尿病
预后
影响因素
抗生素
血清炎性因子
severe pneumonia
concomitant diabetes
prognosis
influencing factors
antibiotics
serum inflammatory factor
