摘要
目的分析医院2018年100例药品不良反应(ADR)发生的规律和特点,为减少临床不良反应的发生提供预防措施。方法从国家不良反应监测网抽取并整理我院2018年1月-2018年12月上报的ADR报告100例,按年龄、性别、给药途径、引起不良反应的药品和累及的器官及临床表现进行分析。结果发生不良反应涉及的药品42种,其中抗感染药物13种,占药品总数的30.95%,占ADR总数的35%;中药制剂9种,占药品总数的21.43%,占ADR总数的25%,给药途径以静脉给药为主,占ADR总数的82%;老年患者易发生药物不良反应,占总例数的42%;不良反应症状以皮肤及附件损伤多见,以轻度不良反应为主。结论进一步加强我院不良反应监测和宣传,加强抗菌药物的管理,减少药品不良反应的发生。
Objective To analyze the regularity and characteristics of ADR in our hospital in 2018,In order to reduce the occurrence of clinical adverse reactions to provide preventive measures.Methods From the National ADR monitoring network,100 ADR reports received by our hospital in January 2018 to December 2018 were extracted and collated.The ADR reports were analyzed by age,sex,route of administration,drug causing adverse reactions,and organ and clinical manifestations.Results 42 kinds of drugs were involved in adverse reactions,of which 13 kinds of antiinfection drugs accounted for 30.95%of the total number of drugs,accounting for 35%of the total ADR;There are 9 kinds of Chinese medicine preparations,accounting for 21.43%of the total number of drugs,accounting for 25%of the total number of ADRs.The main route of administration is intravenous infusion,accounting for 82%of the total number of ADRs;The elderly patients are prone to adverse drug reactions,accounting for 42%of the total number of cases.The symptoms of adverse reactions are more common in skin and accessories,and mild adverse reactions are the main ones.Conclusion further strengthen our hospital adr monitoring and publicity,strengthen the management of antibiotics,reduce the occurrence of adverse drug reactions.
作者
包中文
孟亚梅
BAO Zhongwen;MENG Yamei(Department of Pharmacy,Ezhou Second Hospital,Ezhou Hubei 436000,China)
出处
《中国继续医学教育》
2020年第27期151-154,共4页
China Continuing Medical Education
关键词
药品不良反应
报告
分析
抗感染药物
静脉给药
合理用药
adverse drug reactions
report
analysis
antiinfection drugs
intravenous infusion
rational use of drug
