摘要
目的:观察腹腔镜子宫腺肌病病灶切除术联合促性腺激素释放激素激动剂治疗子宫腺肌病患者的效果。方法:选取96例子宫腺肌病患者作为研究对象,依据随机数字表法将其分为对照组和观察组各48例,对照组采用腹腔镜子宫腺肌病病灶切除术治疗,观察组在对照组基础上联合促性腺激素释放激素激动剂治疗,比较两组生殖激素指标水平、痛经程度、子宫体积、治疗前后月经量、术后并发症/不良反应发生率及随访6个月的复发率。结果:治疗后,观察组雌二醇水平和视觉模拟评分均明显低于对照组,促黄体生成素和卵泡刺激素水平均明显高于对照组,子宫体积明显小于对照组,月经量明显少于对照组,差异均有统计学意义(P<0.05);两组术后并发症/不良反应发生率比较,差异无统计学意义(P>0.05);观察组复发率为0,明显低于对照组的12.50%(6/48),差异有统计学意义(P<0.05)。结论:腹腔镜子宫腺肌病病灶切除术联合促性腺激素释放激素激动剂治疗子宫腺肌病患者的效果优于单纯腹腔镜子宫腺肌病病灶切除术治疗效果。
Objective:To observe effects of laparoscopic adenomyosis lesion resection combined with gonadotropin releasing hormone agonists in treatment of patients with adenomyosis.Methods:96 patients with adenomyosis were selected as the research objects,and divided into control group and observation group according to the random number table method,48 cases in each.The control group was treated with laparoscopic adenomyosis,while the observation group was treated with gonadotropin releasing hormone agonists on the basis of that of the control group.The levels of reproductive hormone indicators,the degree of dysmenorrhea and uterine volume,menstrual volume before and after the treatment,the incidence of postoperative complications/adverse reactions,and the recurrence rate during the 6-month follow-up were compared between the two groups.Results:After the treatment,the estradiol level and visual analog pain score of the observation group were significantly lower than those of the control group;the levels of luteinizing hormone and follicle stimulating hormone were significantly higher than those of the control group;the uterus volume was significantly smaller than that of the control group;the menstrual volume was significantly less than that of the control group;and the differences were statistically significant(P<0.05).There was no significant difference in the incidence of postoperative complications/adverse reactions between the two groups(P>0.05).The recurrence rate of the observation group was 0,which was significantly lower than the 12.50%(6/48)of the control group,and the difference was statistically significant(P<0.05).Conclusions:Laparoscopic adenomyosis lesion resection combined with gonadotropin releasing hormone agonists in the treatment of the patients with adenomyosis is significantly effective with higher safety.
作者
刘榴
LIU Liu(Department of Obstetrics and Gynecology of the Third People’s Hospital of Liaoyang,Liaoyang 111000 Liaoning,China)
出处
《中国民康医学》
2020年第16期6-8,共3页
Medical Journal of Chinese People’s Health
