摘要
目的探究尖锐湿疣患者的情绪、生活质量和复发情况的影响。方法选取2016年7月至2018年4月第四军医大学西京皮肤医院收治的120例尖锐湿疣患者作为研究对象。对患者进行艾拉光动力联合积极护理干预进行治疗。采用焦虑自评量表(SAS)和抑郁自评量表(SDS)观察两组患者治疗前后的情绪变化,采用SF-36量表对患者治疗前后的生活质量变化进行观察,然后6个月后进行随访,对复发和未复发的人群进行分组,调查影响患者复发的影响因素。结果治疗后,患者的焦虑和抑郁的状态比治疗前明显降低;治疗后患者的生活质量明显提高,差异均具有统计学意义(均P<0.05);单因素分析显示,复发组和非复发组患者在年龄、文化程度和吸烟等方面比较,差异无统计学意义(P>0.05),但是复发组在T细胞亚群异常、皮损数量多发和熬夜方面都多于非复发组,差异具有统计学意义(P<0.05)。多因素分析T细胞亚群异常、皮损数量多发和熬夜是尖锐湿疣复发的独立危险因素,差异具有统计学意义(P<0.05)。结论治疗后,尖锐湿疣患者的焦虑和抑郁程度减轻,生活质量明显提高,尖锐湿疣患者复发的危险因素包括T细胞亚群异常、皮损数量多发和熬夜等,可以针对以上的独立危险因素进行针对性的防治。
Objective To explore the influence of emotion,quality of life and recurrence of condyloma acuminatum(CA)patients.Methods 120 CA patients admitted to Xijing Dermatology Hospital of the Fourth Military Medical University from July 2016 to April 2018 were selected and treated by the combination of Ela photodynamic therapy and active nursing intervention.Self-rating Anxiety Scale(SAS)and Self-rating Depression Scale(SDS)were used to observe the emotional changes of the two groups before and after treatment.The SF-36 scale was used to observe the quality of life of the patients before and after treatment.After 6 months of follow-up,the relapsed and non-relapsed groups were grouped and the influencing factors of relapse were investigated.Results After treatment,the state of anxiety and depression of patients was significantly lower than that before treatment and the quality of life of patients was significantly improved,with statistically significant differences(all P<0.05).Univariate analysis showed that there was no significant difference in age,education level and smoking between relapse group and non-relapse group(P>0.05),but the number of abnormal T cell subsets,skin lesions and staying up late in relapse group were higher than those in non-relapse group(P<0.05).Multivariate analysis showed that abnormal T cell subsets,multiple lesions and staying up late were independent risk factors for the recurrence of CA(P<0.05).Conclusions After treatment,the degree of anxiety and depression of CA patients was alleviated,and the quality of life was significantly improved.The risk factors for recurrence of CA included abnormal T cell subsets,multiple lesions and staying up late,according to which targeted prevention and treatment should be taken.
作者
金莹莹
张美霞
李丽
黄晨曦
JIN Yingying;ZHANG Meixia;LI Li;HUANG Chenxi(Xijing Dermatology Hospital of the Fourth Military Medical University,Xi'an 710032,Shaanxi,China;Nursing Department,Air Force Military Medical University First Affiliated Xijing Hospital,Xi'an 710032,Shaanxi,China)
出处
《中国性科学》
2020年第8期142-146,共5页
Chinese Journal of Human Sexuality
基金
陕西社会发展科技攻关项目(2016SF-412)。
关键词
尖锐湿疣
情绪
生活质量
复发因素
Condyloma acuminatum(CA)
Emotion
Quality of life
Influencing factors of recurrence
