摘要
低共熔溶剂(DESs)因具有制备简单、价格低廉、环境友好、挥发性低、溶解能力强、结构可设计、易生物降解等特点,被认为是一种新型的绿色溶剂,在很多领域中有着诱人的应用前景。近年来,DESs已被用于中药活性成分的提取(如黄酮、皂苷、多糖、生物碱、醌类、酚酸、挥发油等)、分离、色谱分析等方面。对DESs的制备和性质及其在中药领域的最新研究成果进行综述,探讨其目前在中药领域应用中存在的问题,并对其发展趋势进行展望。
Deep eutectic solvents(DESs), as a class of novel green solvents, show the promising applications in many fields due to their unique properties such as simple preparation, low cost, environmental friendliness, low volatility, high dissolution power, feasibility of structural design and biodegradability. Recently, DESs have been applied for the extraction, separation and chromatography of active components(flavonoids, saponins, polysaccharides, alkaloids, quinones, phenolic acids, volatile oil, etc) from Chinese materia medica. This article introduced the preparation and properties of DESs, reviewed the development of DESs applications in the field of traditional Chinese medicine, discussed the existing problems and outlined the general trends as well.
作者
王继龙
陈方圆
刘晓霞
魏舒畅
WANG Ji-long;CHEN Fang-yuan;LIU Xiao-xia;WEI Shu-chang(Gansu Engineering Research Center for Chinese Medicine Pharmaceutical Technology,Gansu University of Chinese Medicine,Lanzhou 730000,China;Gansu Health Vocational College,Lanzhou 730207,China)
出处
《中草药》
CAS
CSCD
北大核心
2020年第17期4559-4567,共9页
Chinese Traditional and Herbal Drugs
基金
国家自然科学基金资助项目(81460608)
甘肃省基础研究创新群体项目(1506RJIA034)
甘肃省高等学校创新能力提升项目(2019A-079)
甘肃中医药大学中青年科研基金项目(ZQ2015-9)。
关键词
低共熔溶剂
绿色溶剂
中药
活性成分
性质
提取
deep eutectic solvents
green solvents
Chinese materia medica
active components
properties
extraction