摘要
目的探讨支气管异物患儿合并气管内肉芽形成的危险因素以及肉芽形成对其它并发症的影响。方法回顾性分析2019年1月至2019年10月西安市儿童医院收治的140例支气管异物患儿的临床资料,将患儿按支气管镜下是否有肉芽形成,分为普通组和肉芽组,分析影响支气管异物患儿气管内肉芽形成的危险因素以及肉芽形成对肺不张、肺气肿及肺部炎症发生率的影响。结果 140例患儿中普通组84例(60%),肉芽组56例(40%)。肉芽组患儿的异物平均滞留时间明显高于普通组患儿,差异有统计学意义(P<0.05)。肉芽组患儿白细胞计数高于普通组患儿,差异有统计学意义(P<0.05)。肉芽组患儿植物性异物的比率高于普通组患儿,差异有统计学意义(P<0.05)。Logistic回归分析显示,异物滞留时间[(OR)=2.104, 95%置信区间(CI):1.804~2.295,P<0.001],白细胞计数[(OR)=1.545, 95%置信区间(CI):1.445~1.805,P=0.03]为支气管异物患儿肉芽形成的危险因素。肉芽组患儿阻塞性肺炎发生率高于普通组患儿,差异有统计学意义(P<0.05)。结论异物在气道的滞留时间,机体炎症反应,是支气管异物患儿气管内肉芽形成的危险因素。伴发肉芽形成的支气管异物患儿阻塞性肺炎的发生率高于普通支气管异物患儿。
Objective To investigate the risk factors and influence of other complications of granuloma formation induced by bionchial foreign bodies in children.Methods Retrospective analysis was performed for the clinical data of the 140 children with bronchial foreign body at Xi′an Children′s Hospital,from January 2019 to October 2019.The patients were divided into the normal group and the granulation group,and the correlative index were compared between the 2 groups.Results Among 140 children,84 cases were in the normal group and 55 cases in the granulation group.The mean foreign body retention time in the granulation group was significantly higher than that in the normal group,and the differences were statistically significant(P<0.05).The numeration of leukocyte in the granulation group was higher than that in the normal group,and the differences were statistically significant(P<0.05).The rate of vegetative foreign body in the granulation group was higher than that in the normal group(P<0.05).After adjusted by regression analysis,2 factors were risk factors for granulation formation.They were foreign body retention time[odds ratio(OR)=2.104,95%confidence interval(CI):1.804~2.295,P<0.001],and the numeration of leukocyte[odds ratio(OR)=1.545,95%confidence interval(CI):1.445~1.805,P=0.03].The incidence of obstructive pneumonia in the granulation group was higher than that in the normal group(P<0.05).Conclusion The retention time of foreign body in the airway and the body inflammatory reaction are the risk factors for the granuloma formation induced by bionchial foreign bodies in children.The incidence of obstructive pneumonia in children with bronchial foreign body accompanied by granulation formation is higher than that in children with common bronchial foreign body.
作者
张悦鸣
王贞
张雯
ZHANG Yue-ming;WANG Zhen;ZHANG Wen(DepartmentⅡof Respiratory Disease,Xi an Children s Hospital,Xi an,Shaanxi 710003,China)
出处
《临床肺科杂志》
2020年第10期1574-1577,共4页
Journal of Clinical Pulmonary Medicine
关键词
支气管异物
肉芽
儿童
危险因素
并发症
bronchial foreign body
granuloma formation
children
risk factors
complications
