摘要
目的讨论普拉洛芬联合玻璃酸钠治疗白内障术后干眼症的临床疗效。方法选取2018年6月—2019年6月该院治疗的白内障手术后干眼症的患者100例,根据患者的入院时间顺序分为两组,在实验组中使用普拉洛芬联合玻璃酸钠治疗,在对照组中使用普拉洛芬治疗。观察两组患者治疗效果、干预前后干眼症状评分、泪膜破裂时间、生活满意度。结果实验组(98.00%)和对照组(82.00%)的治疗效果差异有统计学意义(χ2=8.228,P<0.05)。在干预后,实验组的干眼症状评分(8.95±0.75)分小于对照组(11.02±1.17)分,差异无统计学意义(t=7.926,P<0.05)。实验组的泪膜破损时间(13.28±1.87)s高于对照组(10.15±1.26)s,差异有统计学意义(t=7.594,P<0.05)。在干预前,实验组的生活满意度评分(6.08±1.15)分与对照组(6.19±1.22)分相比,差异无统计学意义(t=0.265,P>0.05)。在干预后7 d,实验组的生活满意度评分(22.17±3.26)分高于对照组(16.92±2.58)分,差异有统计学意义(t=7.229,P<0.05)。在干预后21 d,实验组的生活满意度评分(33.25±6.28)分高于对照组(25.83±5.75)分,差异有统计学意义(t=7.832,P<0.05)。结论在白内障手术后干眼症的患者中使用普拉洛芬联合玻璃酸钠治疗,可以提高治疗效果,缓解干眼症状,提高泪膜破裂时间,提高生活满意度,具有重要的临床价值。
Objective To discuss the clinical efficacy of pranoprofen combined with sodium hyaluronate in the treatment of dry eye after cataract surgery.Methods A total of 100 patients with dry eye after cataract surgery treated in our hospital from June 2018 to June 2019 were selected.They were divided into two groups according to the order of patients'admission time,and pranoprofen combined with sodium hyaluronate was used in the experimental group,pranoprofen treatment in the control group.The treatment effect,dry eye symptom score before and after intervention,tear film rupture time and life satisfaction were observed.Results The treatment effect of the experimental group(98.00%)and the control group(82.00%),the difference was statistically significant(χ2=8.228,P<0.05).After the intervention,the dry eye symptom score(8.95±0.75)points of the experimental group was smaller than that of the control group(11.02±1.17)points,the difference wa sstatistically significant(t=7.926,P<0.05).The tear film damage time(13.28±1.87)s in the experimental group was higher than that in the control group(10.15±1.26)s,the difference was statistically significant(t=7.594,P<0.05).Before intervention,the life satisfactioncore of the experimental group(6.08±1.15)points was not statistically different from that of the control group(6.19±1.22)points,the difference was not statistically significant(t=0.265,P>0.05).7 days after the intervention,the life satisfactioncore of the experimental group(22.17±3.26)points was higher than that of the control group(16.92±2.58)points,the difference was statistically significant(t=7.229,P<0.05).At 21 days after the intervention,the life satisfactionscore of the experimental group(33.25±6.28)points was higher than that of the control group(25.83±5.75)points,the difference was statistically significant(t=7.832,P<0.05).Conclusion The use of pranoprofen combined with sodium hyaluronate in patients with dry eye after cataract surgery can improve the treatment effect,relieve dry eye symptoms,increase the tear film rupture time,and improve life satisfaction.It has important clinical value.
作者
李蓉煜
LI Rong-yu(Department of Ophthalmology,Second People's Hospital of Chengyang District,Qingdao,Shandong Province,266112 China)
出处
《系统医学》
2020年第16期7-9,共3页
Systems Medicine
