摘要
地佐辛是术后镇痛常用药物,可单独用于术后轻、中度疼痛的镇痛,也可与非甾体类抗炎药(NSAIDs)、强效阿片类药物等复合用于术后重度疼痛的镇痛;该药还可作为外周神经阻滞、局部浸润麻醉镇痛不足的补救用药。复合用药时,因为镇痛药剂量降低以及药物对各种类型阿片受体的作用不同,呼吸抑制和成瘾等副作用较少,是突出的优点。该药虽广泛应用于术后镇痛,甚至用于术中镇痛,但仍缺乏建立在循证医学基础上的评价,仍需进一步严格对照研究。
作者
张利东
徐建国
王国林
马虹
闵苏
缪长虹
左明章
杨建军
刘克玄
袁红斌
鲍红光
顾连兵
孙杰
Zhang Lidong;Xu Jianguo;Wang Guolin;Ma Hong;Min Su;Miao Changhong;Zuo Mingzhang;Yang Jianjun;Liu Kexuan;Yuan Hongbin;Bao Hongguang;Gu Lianbing;Sun Jie(Department of Anesthesiology,General Hospital of Eastern Theater Command,PLA,Nanjing 210002,China;Department of Anesthesiology,Tianjin Medical University General Hospital,Tianjin 300052,China;Department of Anesthesiology,the First Hospital of China Medical University,Shenyang 110001,China;Department of Anesthesiology,the First Affiliated Hospital of Chongqing Medical University,Chongqing 400016,China;Department of Anesthesiology,Fudan University Shanghai Cancer Center,Shanghai 200032,China;Department of Anesthesiology,Beijing Hospital,Beijing 100730,China;Department of Anesthesia and Perioperative Medicine,the First Affiliated Hospital of Zhengzhou University,Zhengzhou 450002,China;Department of Anesthesiology,Nanfang Hospital,Southern Medical University,Guangzhou 510515,China;Department of Anesthesiology,Shanghai Changzheng Hospital,Shanghai 200071,China;Department of Anesthesiology and Pain,Nanjing First Hospital Nanjing First Hospital,Nanjing Medical University,Nanjing 210006,China;Department of Anesthesiology,Jiangsu Cancer Hospital Jiangsu Institute of Cancer Research Nanjing Medical University Affiliated Cancer Hospital,Nanjing 210009,China;Department of Anesthesiology,Jiangsu Province Hospital the First Affiliated Hospital of Nanjing Medical University,Nanjing 210029,China)
出处
《中华麻醉学杂志》
CAS
CSCD
北大核心
2020年第6期641-645,共5页
Chinese Journal of Anesthesiology