摘要
目的分析河南省乙型肝炎(乙肝)流行特征,为制定乙肝防控措施和评价免疫效果提供参考依据。方法从中国疾病预防控制信息系统获取2004—2019年河南省乙肝疫情数据,用描述性流行病学方法对流行特征进行分析。结果 2004—2019年河南省累计报告乙肝病例1 735 131例,年均报告发病率105.37/10万,2004—2007年乙肝报告发病率整体呈上升趋势,2008—2012年乙肝报告发病率整体呈下降趋势,2013年乙肝报告发病率明显下降;未分型乙肝构成比逐渐降低,2013年之后报告的病例以慢性乙肝为主;报告病例数居前3位为郑州市、南阳市、信阳市,构成比分别为11.30%、10.26%、7.55%;乙肝发病无明显季节性,男性明显高于女性,职业构成以农民为主(63.41%),0岁年龄组累计报告2 026例,平均发病率9.88/10万,25~30岁年龄组年均发病率最高,206.73/10万。结论河南省乙肝报告质量提高,报告发病率呈下降趋势,但报告病例数较高,建议开展乙肝疫苗接种、乙肝母婴阻断项目同时,开展乙肝报告质量的专题研究,进一步提高报告质量,了解乙肝真实发病水平。
Objective To analyze the epidemiological characteristics of hepatitis B in Henan province, and provide evidence for the hepatitis B prevention and control and the evaluation of immunization effects. Methods The incidence data of hepatitis B in Henan from 2004 to 2019 were obtained from National Diseases Reporting Information System for a descriptive epidemiological analysis. Results A total of 1 735 131 cases of hepatitis B were reported in Henan from 2004 to 2019, with an annual average incidence of 105.37 per 100 000. The overall reported incidence of hepatitis B showed an upward trend from2004 to 2007, but showed a downward trend from 2008 to 2012 and showed a significant decline in 2013. The proportion of unclassified hepatitis B cases gradually decreased. The cases reported after 2013 were mainly chronic hepatitis B. The top three areas reporting high hepatitis B case numbers were Zhengzhou, Nanyang, and Xinyang, where the reported cases accounted for11.30%, 10.26% and 7.55% of the total, respectively. There was no obvious seasonality in the reported incidence of hepatitis B.More cases were reported in men than in women with a gender ratio of the cases was 1.47∶1. The majority of the reported cases were farmers(63.41%). A total of 2 026 cases were reported in 0-year-old group with an average reported incidence rate of 9.88/100 000. The annual average reported incidence rate in 25–30-year-old group was highest(206.73/100 000).Conclusion The quality of hepatitis B reported in Henan had been further improved since 2013. The reported incidence of hepatitis B was in decline, but the number of reported cases was still high. It is suggested to conduct special analysis and research on the quality of hepatitis B reporting to improve the reporting quality and understand the actual incidence level of hepatitis B while carrying out hepatitis B vaccination and hepatitis B maternal-neonatal transmission blocking projects.
作者
李军
姬艳芳
杨凯朝
赵东阳
郭永豪
史鲁斌
叶莹
王三凤
张延炀
Li Jun;Ji Yanfang;Yang Kaichao;Zhao Dongyang;Guo Yonghao;Shi Lubin;Ye Ying;Wang Sanfeng;Zhang Yanyang(Henan Provincial Center for Disease Control and Prevention,Zhengzhou 450016,Henan,China;Jiaozuo Prefectural Center for Disease Control and Prevention,Jiaozuo 454100,Henan,China)
出处
《疾病监测》
CAS
2020年第8期766-769,共4页
Disease Surveillance
基金
中国肝炎防治基金会项目(No.YGFK20180078)。
关键词
乙型肝炎
报告质量
流行特征
疫情分析
河南省
Hepatitis B
Reporting quality
Epidemiological characteristics
Incidence analysis
Henan province
