摘要
目的评价丙泊酚全凭静脉麻醉和七氟醚吸入麻醉对肝炎肝硬化围术期凝血功能的影响。方法本院接收行肝癌切除术的肝炎肝硬化患者50例,选入时间为2015年2月—2019年3月。以区组随机化形式分为研究组和对照组,研究组25例行七氟醚吸入麻醉,对照组25例行全凭静脉麻醉,观察两组凝血功能指标。结果两组麻醉前凝血功能指标无对比性,P>0.05,诱导结束、手术结束后,研究组数据较麻醉前无差异,P>0.05,对照组凝血酶原时间、凝血酶凝固时间、D-二聚体、纤维蛋白原、活化部分凝血活酶时间较麻醉前变化显著,两组指标对比差异显著,P<0.05,凝血酶原活动度无明显变化,P>0.05。结论临床将全凭静脉麻醉和七氟醚吸入麻醉比较,七氟醚吸入麻醉对肝炎肝硬化围术期凝血功能的影响比全凭静脉麻醉更小,术后恢复更加有效,医疗纠纷发生率显著降低。
Objective To evaluate the effect of propofol intravenous anesthesia and sevoflurane inhalation anesthesia on perioperative coagulation function of hepatitis cirrhosis.Methods Fifty patients with hepatitis cirrhosis who underwent liver cancer resection were enrolled in this hospital.The enrollment time was from February 2015 to March 2019.The study group and the control group were divided into randomized groups.Twenty-five patients in the study group underwent sevoflurane inhalation anesthesia,and 25 patients in the control group underwent total anesthesia.The coagulation function indexes of the two groups were observed.Results There was no contrast in the coagulation function before anesthesia in the two groups,P>0.05.After the end of induction and after the end of surgery,there was no difference in the data of the study group compared with that before anesthesia,P>0.05,prothrombin time,thrombin coagulation time,D dimer,fibrinogen and activated partial thromboplastin was significantly higher than that before anesthesia.There was significant difference between the two groups,P<0.05,there was no significant change in prothrombin activity,P>0.05.Conclusion Clinically,intravenous anesthesia and sevoflurane inhalation anesthesia are compared.The effect of sevoflurane inhalation anesthesia on perioperative coagulation function of hepatitis cirrhosis is smaller than that of total intravenous anesthesia.The postoperative recovery is more effective and the incidence of medical disputes is significantly reduced.
作者
窦雅丽
杨付明
DOU Yali YANG Fuming(Department of Anesthesiology,Guyuan People's Hospital,Guyuan Ningxia 756000,China)
出处
《中国继续医学教育》
2020年第29期144-147,共4页
China Continuing Medical Education
关键词
全凭静脉麻醉
七氟醚吸复合麻醉
肝炎
肝硬化
凝血功能
效果分析
total intravenous anesthesia
sevoflurane inhalation combined anesthesia
hepatitis
cirrhosis
coagulation function
effect analysis
