摘要
目的分析新型冠状病毒肺炎(COVID-19)患者的CT影像特征,为临床实践提供参考。方法计算机检索PubMed、外文医学信息资源检索平台(FMRS)、EMbase、中国知网(CNKI)和万方数据等数据库,搜集报道COVID-19患者CT影像特征的文献,检索时限为2020年1月1日至3月4日。由2名研究员独立筛选文献、收集数据并评价纳入研究的偏倚风险后,采用Stata12.0软件进行Meta分析。结果共纳入20项回顾性研究,共计1982例COVID-19患者。分析结果显示:COVID-19患者肺部病灶多为双肺受累(68.2%,95%CI:61.1%~74.9%)、多肺叶受累(76.7%,95%CI:56.2%~86.2%),15.6%的患者CT无异常表现。病灶密度改变最常见的为磨玻璃样变(69.8%,95%CI:53.1%~84.1%),其他还有实变(42.9%)、空气支气管征(32.9%)和铺路石征(11.2%)。病灶形态有斑片状(40.6%)、条索状(45.2%)、结节状(43.9%)和网格状(29.0%)。部分患者有胸膜肥厚(32.5%),极少数患者合并有胸腔积液(4.2%)。结论COVID-19患者肺部病灶以双肺或多肺叶受累多见,最常见的表现为斑片状、磨玻璃样变,部分患者出现实变、空气支气管征和胸膜肥厚等,胸腔积液少见。
Objective To systematically review the CT imaging features of COVID-19 so as to provide reference for clinical practice.Methods PubMed,EMbase,CNKI and WanFang databases were electronically searched to collect studies about the CT imaging features of COVID-19 from January,2020 to March 4,2020.Two reviewers independently screened literature,extracted data and assessed the risk of bias of included studies,then,meta-analysis was performed by using Stata12.0 software.Results A total of 20 retrospective studies involving 1982 COVID-19 patients were included.The results of meta-analysis showed that most patients presented bilateral lung(68.2%,95%CI:61.1%-74.9%)or multiple lung lobes(76.7%,95%CI:56.2%-86.2%)lesions,and the ratio of normal CT findings was 15.6%.The most common changes in lesion density were ground-glass opacities(69.8%,95%CI:53.1%-84.1%).Other changes in density included consolidation(42.9%),air bronchogram sign(32.9%)and crazy-paving pattern(11.2%).Patchy(40.6%),cord-like(45.2%),nodular(43.9%)and spider web sign(29.0%)were common lesion shapes in COVID-19 patients.Pleural thickening(32.5%)was found in some patients and pleural effusion(4.2%)was rare.Conclusion The lung lesions of patients with COVID-19 were mostly affected by bilateral or multiple lobes.The most common chest CT findings were patchy and ground-glass opacities.Some patients had consolidation,air bronchogram and pleura hypertrophy,and pleural effusion was not common.
作者
钟枝梅
朱洁云
李柏成
吉攀
李红园
何翠影
庞杰龙
张剑锋
ZHONG Zhimei;ZHU Jieyun;Li Bocheng;JI Pan;LI Hongyuan;HE Cuiying;PANG Jielong;ZHANG Jianfeng(Department of Emergency,the Second Affiliated Hospital of Guangxi Medical University,Nanning,Guangxi 530007,China)
出处
《重庆医学》
CAS
2020年第19期3165-3171,共7页
Chongqing medicine
基金
广西重点研发计划防控新型冠状病毒感染肺炎疫情应急科技攻关专项(桂科AB20058002)。
关键词
新型冠状病毒肺炎
CT
影像特征
META分析
COVID-19
computed tomography
imaging features
Meta-analysis
systematical review
