摘要
目的探讨两种不同检测系统对肿瘤标志物(AFP、CEA)的测定结果是否存在可比性。方法采用CLSI EP9-A2方案对两种不同检测系统检测的肿瘤标志物结果进行比对和偏差评估。结果两种检测系统对AFP和CEA检测结果经验证具有可比性,在临界值水平均有较明显偏差,可能导致阴阳性不一致的情况,在其他医学决定水平一致性良好,能够被临床所接受。结论在同一个实验室内使用不同检测系统检测肿瘤标志物时,务必进行结果的比对和偏差评估,以保证结果的可比性。
Objective To explore the comparability of the results of two different detection systems for tumor markers(AFP,CEA).Methods CLSI EP9-A2 scheme was used to compare and evaluate the results of tumor markers detected by two different detection systems.Results The results showed that the two detection systems had a comparability for AFP and CEA detections,while an obvious deviation at the critical level was observed,which could lead to the inconsistency of negative and positive rates between two systems.The consistency at other medical decision levels was good,and could be accepted by the clinic.Conclusion When using different detection systems to detect tumor markers in the same laboratory,it is necessary to compare the results and evaluate the deviation,so as to ensure the comparability of the results.
作者
于丽莎
郝铁
YU Lisha;HAO Tie(Department of Laboratory,Anshan Central Hospital,Anshan 114001,China)
出处
《标记免疫分析与临床》
CAS
2020年第9期1627-1631,共5页
Labeled Immunoassays and Clinical Medicine
关键词
肿瘤标志物
可比性分析
偏倚评估
Tumor markers
Comparative analysis
Biases estimation
