摘要
女性避孕节育药具是指通过影响女性生殖过程的不同环节,从而达到抗生育目的的药物和器具。自20世纪60年代首个女性避孕药上市至今,经过数十年的发展,女性避孕节育药具不仅在提高避孕成功率、减轻不良反应方面有了很大进步,而且在发挥避孕作用时,还可对子宫内膜异位症、原发性痛经、月经不调等具有一定治疗作用。该文综述临床常用女性避孕节育药具发展历程,总结分析女性避孕节育药具研究现状,以期为女性避孕节育药具的研究开发及应用提供参考。
Female contraceptives are medicines or apparatus which can be used to achieve the purpose of anti-fertility by affecting different periods of the reproductive cycle.About 60 years have passed since the first female contraceptive Enovid^®was approved in the 1960s.With the development of technology,new drugs were discovered.These drugs possess higher success rate of contraception and lower side effects.Furthermore,some of them even have therapeutic effect on endometriosis,primary dysmenorrhea and irregular menstruation.This article reviewed and analyzed the current use of female contraceptives,looking forward to providing some useful information for the development of relevant products.
作者
胡堃
张丽
张宝喜
杨德智
吕扬
HU Kun;ZHANG Li;ZHANG Baoxi;YANG Dezhi;LYU Yang(Beijing Key Laboratory of Polymorphic Drugs,Institute of Materia Medica,Chinese Academy of Medical Sciences & Peking Union Medical College,Beijing100050,China)
出处
《医药导报》
CAS
北大核心
2020年第11期1506-1510,共5页
Herald of Medicine
基金
国家重点研发计划(2016YFC1000900)
国家科技重大专项-重大新药创制(2017ZX09101001,2018ZX09711001-010)
中国医学科学院医学与健康科技创新工程(2017-I2M-1-010)
国家自然科学基金资助项目(81703473)。
关键词
女性避孕药
紧急避孕药
短效避孕药
长效避孕药具
口服避孕药
Female contraceptives
Emergency contraception
Short-acting contraceptives
Long-acting contraceptives and devices
Oral contraceptives