摘要
脑血管疾病是目前严重危害人类健康的主要疾病之一,是我国致残率最高的疾病。脑卒中的后期康复是目前临床亟需解决的重点及难点问题。针刺治疗在脑卒中后期的康复中具有一定的特色、优势且疗效显著,但是其作用机制目前仍不清楚,研究表明针刺治疗脑卒中的作用机制可能与脑的可塑性有关。本研究从突触概述、针刺对突触结构、突触功能及突触相关蛋白影响角度出发,整理分析针刺对脑卒中后突触可塑性的影响,为针刺治疗脑卒中的康复机制提供理论基础及科学依据。
Cerebrovascular disease is one of the major diseases that seriously endanger human wellbeing at present and has the highest disability rate in China.The rehabilitation of cerebral apoplexy has been a key and difficult problem in clinical practice in recent years.Acupuncture therapy has significant advantages in the rehabilitation of the patients with stroke,but its action mechanism is still unclear.Studies have shown that the mechanism of acupuncture is related to brain plasticity,and synaptic plasticity is the core of brain plasticity.In this study,the influence of acupuncture on synaptic plasticity after stroke was analyzed in terms of synapse overview and the influence of acupuncture to synaptic structure,synaptic function and synaptic related proteins,so as to provide theoretical basis and scientific basis for the rehabilitation mechanism of acupuncture in the treatment of stroke.
作者
王东岩
杨海永
董旭
路思宇
麻聪聪
WANG Dongyan;YANG Haiyong;DONG Xu;LU Siyu;MA Congcong(Heilongjiang University of Chinese Medicine, Harbin 150040, China;The Second Affiliated Hospital of Heilongjiang University of Chinese Medicine, Harbin 150001, China;Shanxi University of Chinese Medicine, Xianyang 711301, China)
出处
《针灸临床杂志》
2020年第10期84-88,共5页
Journal of Clinical Acupuncture and Moxibustion
基金
国家自然科学基金,编号:81473763
黑龙江中医药大学创新团队建设项目,编号:2017sit01
黑龙江省中医药中青年科技攻关项目,编号:ZQG-028
黑龙江中医药大学研究生创新科研项目,编号:2018yjscx012。
关键词
针刺
脑卒中
突触
突触可塑性
Acupuncture
Stroke
Synapse
Synaptic plasticity
