摘要
目的:分析检测慢性阻塞性肺疾病急性加重期(AECOPD)患者血清降钙素原水平的临床意义。方法:选取2017年1月-2020年4月AECOPD住院患者80例,按入院顺序分为两组,各40例。对照组进行血常规检测,根据患者生命体征、临床表现以及实验室检查结果判断是否需要使用抗生素治疗;试验组在血常规检测基础上检测血清降钙素原(PCT)与超敏C反应蛋白(hs-CRP)指标水平。比较两组抗生素使用时间、住院时间与二重感染发生率。结果:试验组hs-CRP检查阳性率为55.0%,PCT检查阳性率为77.5%。试验组抗生素使用时间、住院时间及二重感染发生率均低于对照组,差异有统计学意义(P<0.05)。结论:将测定血清PCT浓度作为判断AECOPD患者是否应用抗生素进行治疗的一个重要指标,具有更快速、更准确等特点。
Objective:To analyze the clinical significance of detecting serum procalcitonin levels in patients with acute exacerbation of chronic obstructive pulmonary disease(AECOPD).Methods:From January 2017 to April 2020,80 cases of AECOPD inpatients were enrolled,they were divided into two groups according to the order of admission,with 40 cases in each group.The control group underwent routine blood tests and judged whether antibiotic therapy is needed based on the patient's vital signs,clinical manifestations and their laboratory test results.The test group detected serum procalcitonin(PCT)and hypersensitive C-reactive protein(hs-CRP)index levels on the basis of routine blood testing.The use time of antibiotic,the length of hospital stays and the incidence rate of double infection between the two groups were compared.Results:The positive rate of hs-CRP test in the test group was 55.0%,the positive rate of PCT test was 77.5%.The duration time of antibiotic use,the length of hospital stays and the incidence rate of double infection in the test group were all lower than in the control group,the differences were statistically significant(P<0.05).Conclusion:The determination of serum PCT concentration is an important indicator for judging whether AECOPD patients should be treated with antibiotics,which has the characteristics of faster and more accurate.
作者
李红梅
Li Hongmei(Changqiao People's Hospital of Wuzhong District,Suzhou City,Jiangsu Suzhou 215128)
出处
《中国社区医师》
2020年第30期118-119,共2页
Chinese Community Doctors
关键词
慢性阻塞性肺疾病
急性加重期
血清降钙素原
超敏C反应蛋白
Chronic obstructive pulmonary disease
Acute exacerbation
Serum procalcitonin
Hypersensitive C-reactive protein
