摘要
目的:分析静脉溶栓治疗对急性缺血性脑卒中患者神经功能、凝血功能指标的影响。方法:回顾分析笔者所在医院2019年4月-2020年3月收治的急性缺血性脑卒中患者40例(观察组),均接受静脉溶栓治疗,同时纳入同时期于笔者所在医院体检的40例健康者作为对照组。比较观察组治疗前后神经功能、凝血功能及脑血流动力学指标变化。比较两组凝血功能及脑血流动力学指标。结果:观察组治疗后NIHSS评分低于治疗前,差异有统计学意义(P<0.05)。观察组治疗后PT、APTT均高于治疗前,FIB、D-D均低于治疗前,差异有统计学意义(P<0.05)。观察组治疗后凝血指标与对照组比较差异无统计学意义(P>0.05)。观察组治疗后Qmin、Vmin均高于治疗前,R低于治疗前,差异有统计学意义(P<0.05),观察组治疗后脑血流动力指标与对照组比较差异无统计学意义(P>0.05)。结论:急性缺血性脑卒中患者接受静脉溶栓治疗,对其神经功能、凝血功能均有明显改善作用。
Objective:To analyze the influence of intravenous thrombolytic therapy on neurological function and coagulation function in patients with acute ischemic stroke.Method:Retrospective analysis of 40 patients with acute ischemic stroke admitted in our hospital from April 2019 to March 2020 (observation group).All patients received intravenous thrombolytic therapy.At the same time,40 healthy subjects who were examined in our hospital were included as the control group.The changes of neurological function,coagulation function and cerebral hemodynamic indexes before and after treatment were compared in the observation group.The coagulation function and cerebral hemodynamic indexes were compared between the two groups.Result:After treatment,NIHSS score of the observation group was lower than that before treatment,and the difference was statistically significant (P<0.05).After treatment,PT and APTT in the observation group were higher than those before treatment,while FIB and D-D were lower than those before treatment,the differences were statistically significant (P<0.05).After treatment,there were no significant differences in coagulation indexes between the observation group and the control group (P>0.05).After treatment,Qmin and Vmin of the observation group were higher than those before treatment,and R was lower than that before treatment,the differences were statistically significant (P<0.05).After treatment,There were no significant differences in cerebral hemodynamic indexes between the observation group and the control group (P>0.05).Conclusion:Intravenous thrombolytic therapy in patients with acute ischemic stroke can significantly improve their neurological function and coagulation function.
作者
雷爱弟
LEI Aidi(Xiamen Fifth Hospital,Xiamen 361101,China)
出处
《中外医学研究》
2020年第28期26-28,共3页
CHINESE AND FOREIGN MEDICAL RESEARCH
关键词
急性缺血性脑卒中
静脉溶栓
神经功能
凝血功能
Acute ischemic stroke
Intravenous thrombolytic
Neurological function
Coagulation function
