摘要
目的研究连续性肾脏替代治疗与间歇性血液透析治疗重症急性肾功能衰竭患者的临床疗效。方法随机挑选我院2011年10月至2018年12月收治的52例重症急性肾功能衰竭患者,根据治疗方法的不同分为对照组(28例)与观察组(24例)。对照组患者进行间歇性血液透析治疗,观察组患者进行连续性肾脏替代治疗。对比两组患者各项监测指标、肾功能指标、并发症发生率。结果观察组患者治疗后血尿乳酸、二氧化碳结合力、酸碱度(pH)、氧分压、二氧化碳分压(PCO2)、凝血活酶时间(APTT)、凝血酶原时间(PT)、纤维蛋白原、凝血酶时间(TT)、尿素氮、男性血清肌酐、女性血清肌酐、血尿酸、尿蛋白试验均优于对照组,并发症发生率低于对照组(P<0.05)。结论重症急性肾功能衰竭患者采用连续性肾脏替代治疗效果明显优于间歇性血液透析治疗,能够有效改善患者的治疗效率,减少并发症,降低病死率,提高生存率。
Objective To study the clinical efficacy of continuous renal replacement therapy and intermittent hemodialysis in the treatment of patients with severe acute renal failure.Methods Fifty-two patients with severe acute renal failure admitted to our hospital from October 2011 to December 2018 were randomly selected and divided into control group(28 cases)and observation group(24 cases)according to different treatment methods.The control group was treated with intermittent hemodialysis,and the observation group was treated with continuous renal replacement therapy.The monitoring indexes,renal function indexes and incidence of complications were compared between the two groups.Results The blood and urine lactic acid,carbon dioxide binding capacity,pH,partial pressure of oxygen,partial pressure of carbon dioxide(PCO2),activated partial thromboplastin time(APTT),prothrombin time(PT),fibrinogen,thrombin time(TT),urea nitrogen,male serum creatinine,female serum creatinine,blood uric acid,urine protein tests in the observation group were better than those in the control group,the incidence of complications in the observation group was lower than that in the control group(P<0.05).Conclusion In patients with severe acute renal failure,the effect of continuous renal replacement therapy is significantly better than that of intermittent hemodialysis,which can effectively improve the treatment efficiency,reduce complications,reduce mortality and improve survival rate.
作者
高华
GAO Hua(Central Hospital of Kuandian Manchu Autonomous County,Dandong 118200,China)
出处
《中国医药指南》
2020年第27期84-85,88,共3页
Guide of China Medicine
关键词
急性肾功能衰竭
连续性肾脏替代治疗
间歇性血液透析
肾功能
并发症
Acute renal failure
Continuous renal replacement therapy
Intermittent hemodialysis
Renal function
Complications
