摘要
目的探讨LEEP环切病理诊断与宫颈液基细胞学检查在宫颈癌及癌前病变筛查中的应用效果,分析其活检结果。方法选取2017年8月至2018年4月于我院接受宫颈癌及癌前病变筛查的60例患者作为研究对象,取宫颈内皮细胞,进行宫颈液基细胞学,同时进行阴道镜活检。在LEEP环切术后,送检病理组织。结果经LEEP环切病理诊断后,阳性检出率为88.33%。经宫颈液基细胞学检查后,其阳性检出结果为91.67%。宫颈液基细胞学方法对于良性反应性改变、不典型鳞状细胞(ASCUS)、低度鳞状上皮内病变(LSIL)以及高度鳞状上皮内病变(HSIL)的检出结果,与LEEP环切病理诊断结果的符合率分别为80.00%、73.91%、72.00%以及85.71%,总符合率为75.00%。阴道镜活检方法对于良性反应性改变、ASCUS、LSIL以及HSIL的检出结果,与LEEP环切病理诊断结果的符合率分别为83.33%、75.00%、65.00%以及80.00%,总符合率为71.67%。结论在宫颈癌及癌前病变筛查工作中,可采用宫颈液基细胞学检查、阴道镜活检等方法进行判断,能够准确检出疾病,但也存在着很高的误诊风险,需要实施LEEP环切病理诊断,对疾病做进一步确诊。
Objective To investigate the effect of LEEP circumcision pathological diagnosis and cervical liquid-based cytology in the screening of cervical cancer and precancerous lesions,and analyze the biopsy results.Methods Sixty patients who underwent cervical cancer and precancerous lesion screening in our hospital from August 2017 to April 2018 were enrolled.Cervical endothelial cells were taken for cervical cytology and colposcopy biopsy was performed.After LEEP circumcision,the pathological tissue was sent for examination.Results After LEEP circumcision pathological diagnosis,the positive detection rate was 88.33%.After cervical liquid-based cytology,the positive result was 91.67%.Cervical fluid-based cytology for the detection of benign reactive changes,atypical squamous cells(ASCUS),low-grade squamous intraepithelial lesions(LSIL),and highly squamous intraepithelial lesions(HSIL),with LEEP circumcision The coincidence rates of pathological diagnosis were 80%,73.91%,72.00%,and 85.71%,respectively,and the total coincidence rate was 75.00%.The colposcopy biopsy method for benign reactivity changes,ASCUS,LSIL and HSIL detection results,and the LEEP circumcision pathological diagnosis results were 83.33%,75.00%,65.00%and 80.00%,the total coincidence rate was 71.67%.Conclusion In the screening of cervical cancer and precancerous lesions,methods such as liquid-based cytology and colposcopy biopsy can be used to make judgment,which can accurately detect the disease,but there is also a high risk of misdiagnosis.Therefore,LEEP circumferential pathological diagnosis should be carried out for further diagnosis of the disease.
作者
范晓明
赵俊军
FAN Xiaoming;ZHAO Junjun(Dalian Central Hospital,Shenyang 116003,China)
出处
《中国医药指南》
2020年第27期115-116,共2页
Guide of China Medicine
关键词
宫颈癌
癌前病变
LEEP环切病理诊断
宫颈液基细胞学
活检结果
Cervical cancer
Precancerous lesions
LEEP circumcision pathological diagnosis
Cervical liquid-based cytology
Examination results
