摘要
目的:探究后路椎间孔镜在腰椎间盘突出患者中的效果及对创伤应激的控制。方法:选取2018年1月-2019年7月本院86例腰椎间盘突出患者作为研究对象,根据手术方式进行分组,后路椎板开窗髓核摘除术为对照组,后路椎间孔镜手术为观察组,每组43例。比较两组治疗后不同时间总优良情况、治疗前后结构参数、VAS评分及血清创伤应激指标前列腺素E2(PGE2)、β-内啡肽(β-EP)及血清皮质醇(Cor)水平。结果:治疗后3、6个月两组总优良率比较,差异均无统计学意义(P>0.05)。治疗前两组结构参数、VAS评分及血清创伤应激指标比较,差异均无统计学意义(P>0.05);治疗后3、6个月两组结构参数比较,差异均无统计学意义(P>0.05),观察组VAS评分情况显著均优于对照组(P<0.05);治疗后1、2周观察组血清创伤应激指标均显著低于对照组(P<0.05)。结论:后路椎间孔镜在腰椎间盘突出患者中的治疗效果较好,且对创伤应激的控制作用较好,在腰椎间盘突出患者中的应用价值较高。
Objective:To study on the effect of posterior percutaneous transforaminal endoscopic and the influence for the control of traumatic stress in patients with lumbar disc herniation.Method:A total of 86 patients with lumbar disc herniation in our hospital from January 2018 to July 2019 were selected as study subjects and grouped according to the surgical method,posterior lamina fenestration resection of the nucleus pulposus was used as the control group and posterior percutaneous transforaminal endoscopic surgery was used as the observation group,43 patients in each group.After treatment,the total good condition,structural parameters,VAS score,and serum traumatic stress indicators,prostaglandins E2(PGE2),β-endorphin(β-EP)and cortisol(Cor)were compared between two groups at different times.Result:There were no significant differences in the total good rates between two groups at 3 and 6 months after treatment(P>0.05).The structural parameters,VAS score and serum traumatic stress indexes of two groups before treatment compared,the differences were not statistically significant(P>0.05);at 3 and 6 months after treatment,the structure parameters of two groups compared,the differences were not statistically significant(P>0.05),the VAS score cases of the observation group was superior to those of the control group(P<0.05);at 1,2 weeks after treatment,the serum traumatic stress index of the observation group were lower than those of the control group,the differences were statistically significant(P<0.05).Conclusion:The posterior percutaneous transforaminal endoscopic has a good therapeutic effect in patients with lumbar disc herniation,and has a good control effect on traumatic stress,so it has a high application value in patients with lumbar disc herniation.
作者
陈孔宁
刘成招
陈恒梅
CHEN Kongning;LIU Chengzhao;CHEN Hengmei(Mindong Hospital Affiliated to Fujian Medical University,Fuan 355500,China)
出处
《中国医学创新》
CAS
2020年第30期72-75,共4页
Medical Innovation of China
关键词
后路椎间孔镜
腰椎间盘突出
创伤应激
Posterior percutaneous transforaminal endoscopic
Lumbar disc herniation
Traumatic stress
