摘要
目的:探讨右美托咪定复合丙泊酚对妇科腹腔镜手术患者麻醉后并发症及肺功能的影响。方法:选取2019年1月至2020年2月200例行妇科腹腔镜手术的患者分为A、B组,均给予全身麻醉,A组给予右美托咪定复合丙泊酚麻醉诱导,B组仅给予丙泊酚麻醉诱导,比较两组肺功能指标、血流动力学指标、不同时间点镇静评分、并发症发生情况。结果:麻醉前两组肺功能指标无显著性差异(P>0.05),麻醉后B组FVC、VCmax、FEV1/FVC等指标明显下降(P<0.05),在不同的时间点,麻醉对于所有患者的HR、MAP、SpO 2均有不同程度的影响,并且T1、T2、T3时间点A组HR较B组显著提高,T2时间点A组MAP较B组显著提高(P<0.05),T0时间点两组Ramsay评分无显著性差异(P>0.05),T1、T2、T3时间点A组Ramsay评分均高于B组(P<0.05),A组肺功能损伤、肺部感染发生率分别为2.00%、3.00%较B组13.00%、13.00%显著降低(P<0.05)。结论:右美托咪定复合丙泊酚应用于妇科腹腔镜手术患者镇静、镇痛效果显著,维持患者的血流动力学指标,降低患者术后并发症和肺部感染的发生率,安全、可靠。
Objective:To investigate and analyze the effects of dexmedetomidine combined with propofol on post-anaesthesia complications and lung function in patients undergoing gynecological laparoscopic surgery;Methods:Select 200 cases of gynecological laparoscopic surgery from February 2019 to June 2020 The patients were divided into groups A and B.Both groups were given general anesthesia.Group A was given dexmedetomidine combined with propofol for induction of anesthesia,and group B was given only propofol for induction of anesthesia.Comparison of lung function indexes before and after anesthesia and different time points between the two groups Hemodynamic indicators,sedation scores at different time points,and complications;Results:There was no significant difference in pulmonary function indicators between the two groups before anesthesia(P>0.05).After anesthesia,FVC,VCmax,FEV1/FVC and other indicators were obvious in group B Decrease(P<0.05).At different time points,anesthesia has different effects on the HR,MAP,and SpO 2 of all patients,and the HR of group A at T1,T2,and T3 is significantly higher than that of the control group.At T2,The MAP of group A was significantly higher than that of the control group(P<0.05).There was no significant difference in Ramsay scores between the two groups at T0 time point(P>0.05).The Ramsay scores of group A at T1,T2,and T3 were all higher than those of the control group(P<0.05).,the incidence of lung function damage and lung infection in group A were 2.00%and 3.00%,respectively,which were significantly lower than those in the control group 13.00%and 13.00%(P<0.05);Conclusion:dexmedetomidine combined with propofol should be used Gynecological laparoscopic surgery patients have significant sedative and analgesic effects,maintain the patient's hemodynamic indicators,and reduce the incidence of postoperative complications and lung infections.It is safe and reliable.
作者
周慧芬
ZHOU Huifen(Zhongshan Guzhen people's Hospital,528421)
出处
《包头医学院学报》
CAS
2020年第8期35-38,共4页
Journal of Baotou Medical College
关键词
右美托咪定
丙泊酚
腹腔镜
肺功能
dexmedetomidine
propofol
laparoscopy
lung function
