摘要
羽叶丁香为我国特有的木犀科丁香属植物,局限分布于内蒙古与宁夏的贺兰山地区,其去皮的根、茎及粗枝为一味特色蒙古族药材山沉香,临床多用于治疗冠心病、心绞痛等心肺疾病。现代研究显示,羽叶丁香主要含木脂素类、倍半萜类和挥发油类成分,具有抗心肌缺血、镇静、镇痛、抗菌等药理活性。近五年来国内多个课题组对羽叶丁香的化学成分与药理活性研究有了新的进展。该文在此前综述的基础上,对新的研究成果归纳总结,为羽叶丁香特别是山沉香的开发研究和临床应用提供有益参考。
Syringa pinnatifolia is an endemic species of Syringa in Oleaceae family in China,mainly distributed in Helan Mountain,which is located between Inner Mongolia and Ningxia.Its peeled roots,stems and thick twigs have been used as Mongolian folk medicine,called"Shan-chen-xiang"in Chinese,for the treatment of coronary heart diseases,angina pectoris and other cardiopulmonary diseases.Modern researches showed that S.pinnatifolia mainly contains lignans,sesquiterpenoids,and volatile oils,and displays anti-myocardial ischemia,sedation,analgesia,antibacterial and other effects.In the past five years,many groups have made new progress on the study of chemical constituents and pharmacological activities of S.pinnatifolia.On the basis of the previous review by our group,this paper summarizes the advances which is beneficial to the development,research and clinical application of S.pinnatifolia,particularly Shan-chen-xiang.
作者
刘长鑫
焦顺刚
周晓春
黎安妮
马晓静
沙娜·吾肯
陈苏依勒
屠鹏飞
柴兴云
LIU Chang-xin;JIAO Shun-gang;ZHOU Xiao-chun;LI An-ni;MA Xiao-jing;WUKEN Sha-na;CHEN Su-yi-le;TU Peng-fei;CHAI Xing-yun(Modern Research Center for Traditional Chinese Medicine,School of Chinese Materia Medica,Beijing University of Chinese Medicine,Beijing 100029,China;Alashan League Mongolian Medicine Hospital,Alxa 750300,China)
出处
《中国中药杂志》
CAS
CSCD
北大核心
2020年第17期4196-4204,共9页
China Journal of Chinese Materia Medica
基金
中央本级重大增减支项目(2060302)
国家自然科学基金项目(81473426)。
关键词
羽叶丁香
化学成分
药理活性
综述
Syringa pinnatifolia
chemical constituents
pharmacological effect
review
