摘要
目的:观察追风透骨胶囊联合西药治疗风湿性关节炎寒湿痹阻证患者的临床疗效。方法:选取封丘县人民医院2018年3月至2019年2月期间收治的100例类风湿性关节炎寒湿痹阻证患者,采用随机数表法分为观察组和对照组,各50例。对照组给予甲氨蝶呤片,观察组在对照组基础上服用追风透骨胶囊,比较两组的疗效,双手平均握力、C反应蛋白、红细胞沉降率以及不良反应发生情况。结果:观察组患者治疗总有效率为94.00%高于对照组的74.00%,差异有统计学意义(P<0.05);治疗前两组患者的双手平均握力、C反应蛋白、红细胞沉降率比较,差异均无统计学意义(P>0.05);治疗后,两组患者的双手平均握力、C反应蛋白、红细胞沉降率均有不同程度改善,且观察组患者双手平均握力较对照组明显提高,C反应蛋白和红细胞沉降率较对照组明显降低,差异均有统计学意义(P<0.05);观察组患者不良反应发生率为16.00%低于对照组的38.00%,差异有统计学意义(P<0.05)。结论:追风透骨胶囊联合西药治疗类风湿性关节炎寒湿痹阻证疗效显著,不良反应少。
Objective To observe the clinical efficacy of Zhuifengtuogu capsule combined with western medicine in the treatment of rheumatic arthritis with cold-dampness obstruction syndrome.Methods 100 patients with rheumatoid arthritis with cold-dampness obstruction syndrome treated in Fengqiu County people’s Hospital from March 2018 to February 2019 were randomly divided into observation group(n=50)and control group(n=50).The control group was given methotrexate tablets,and the observation group was given Zhuifengtuogu capsule on the basis of the control group.The curative effect,average grip strength of both hands,C-reactive protein,erythrocyte sedimentation rate and adverse reactions were compared between the two groups.Results The total effective rate of the observation group was 94.00%,which was significantly higher than that of the control group(74.00%)(P<0.05).There was no significant difference in average grip strength,C-reactive protein and erythrocyte sedimentation rate between the two groups before treatment(P>0.05).After treatment,the average grip strength,C-reactive protein and erythrocyte sedimentation rate of the two groups were improved in varying degrees,and the average grip strength of the observation group was significantly higher than that of the control group,while the C-reactive protein and erythrocyte sedimentation rate of the observation group were significantly lower than those of the control group(P<0.05).The difference was statistically significant(P<0.05).The incidence of adverse reactions in the observation group(16.00%)was significantly lower than that in the control group(38.00%)(P<0.05).Conclusion Zhuifeng Tougu capsule combined with western medicine is effective in the treatment of cold-dampness obstruction syndrome of rheumatoid arthritis and reduces adverse reactions.
作者
郭岩林
何佳
GUO Yan-lin;HE Jia(People's Hospital ofFengqiu County,Henan Fengqiu 453300;Xinxiang County Central Hospital,Henan Xinxiang 453099)
出处
《深圳中西医结合杂志》
2020年第19期16-18,共3页
Shenzhen Journal of Integrated Traditional Chinese and Western Medicine
基金
河南省医学科技攻关计划项目资助课题(201701037)。
关键词
类风湿性关节炎
寒湿痹阻证
追风透骨胶囊
Rheumatoid arthritis
Cold-dampness obstruction syndrome
Zhuifengtuogu capsule
